Evidence map›Paper›PMID 39600378›Full record

ArticleAJP reports2024

Cardiac Dysfunction Associated with Lacosamide in a Premature Infant with Hypoxic Ischemic Encephalopathy: A Case Report.

Trassanee Chatmethakul, Amy H Stanford, Danielle R Rios, Adrianne R Bischoff, Theresa Czech, Patrick J McNamara

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in AJP reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Trassanee ChatmethakulDepartment of Pediatrics, Neonatal-Perinatal Medicine Section, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.ORCID 0000-0002-5988-9030
Amy H StanfordDivision of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, Iowa.
Danielle R RiosDivision of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, Iowa.
Adrianne R BischoffDivision of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, Iowa.
Theresa CzechPediatric Neurology Division, Department of Pediatrics, University of Iowa, Iowa City, Iowa.
Patrick J McNamaraDivision of Neonatology, Department of Pediatrics, University of Iowa, Iowa City, Iowa.ORCID 0000-0001-7648-8872

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lacosamide (Vimpat Harris FRC Corporation, 2022 UCB, Inc. Smyrna, GA 30080) is an antiseizure medication, which acts through blockage of voltage-gated neuronal sodium channels. Its recent implementation in the neonatal population has been extrapolated from adult and pediatric data suggesting a favorable safety profile. Of note, preterm infants have unique developmental characteristics that may predispose them to increased risk of adverse reactions. We present a case of a preterm neonate who developed left ventricular dysfunction coinciding with the initiation of lacosamide.

Indexed as

antiseizure medicationcardiac dysfunctionlacosamidepreterm infant

Identifiers

PMID39600378
PMCPMC11597592

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.