Evidence map›Paper›PMID 39600531›Full record

ReviewClinical, cosmetic and investigational dermatology2024

Implications of pH and Ionic Environment in Chronic Diabetic Wounds: An Overlooked Perspective.

Jing Guo, Yi Cao, Qing-Yuan Wu, Yi-Mai Zhou, Yuan-Hao Cao, Lu-Sha Cen

Abstract readReview
In one paragraph

Review in Clinical, cosmetic and investigational dermatology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Negative Pressure Wound Therapy Modulates Wound pH and Bacterial Invasion inPlastic and reconstructive surgery. Global open · 2026
    Article
  5. Review
  6. A sequentially programmed FeMaterials today. Bio · 2026
    Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing GuoDepartment of Dermatology. The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ZheJiang Province, People's Republic of China.ORCID 0009-0003-7826-3628
Yi CaoDepartment of Dermatology. The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ZheJiang Province, People's Republic of China.
Qing-Yuan WuDepartment of Respiratory & Critical Care Medicine.The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ZheJiang Province, People's Republic of China.
Yi-Mai ZhouThe First Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang Province, People's Republic of China.
Yuan-Hao CaoThe First Clinical Medical College, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang Province, People's Republic of China.
Lu-Sha CenDepartment of Ophthalmology. The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, ZheJiang Province, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high incidence of disability and fatality rates associated with chronic diabetic wounds are difficult problems in the medical field. The steady-state and regular changes of the microenvironment in and around the wound provide good conditions for wound healing and achieve a dynamic and complex process of wound healing.The pH value and ionic environment composed of a variety of ions in wound are important factors affecting the wound microenvironment, and there are direct or indirect connections between them. Abnormalities in pH, ion concentrations, and channels in skin tissue may be one of the reasons for the high incidence and difficulty in chronic diabetic wounds healing. Currently, different wound-dressing applications have been developed based on the efficacy of ions. Here, the effect of pH in wounds, concentrations of calcium (Ca

Indexed as

Chronic diabetic woundsIonic environmentIonspHReviewWound healing

Identifiers

PMID39600531
PMCPMC11590674

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.