Evidence map›Paper›PMID 39601167›Full record

ReviewMicroRNA (Shariqah, United Arab Emirates)2026

The Role of Noncoding RNAs in the Prognosis and Diagnosis of Colorectal Cancer: An Emerging Biomarker.

O Surekha Vani, Kavitha R Thangaraj, Varshaa Ravichandran, Solomon F D Paul

Abstract readReview
PubMed Publisher
In one paragraph

Review in MicroRNA (Shariqah, United Arab Emirates), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

O Surekha VaniDepartment of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (Deemed University), Porur, Chennai, 600116, Tamil Nadu, India.ORCID 0009-0009-6817-2427
Kavitha R ThangarajDepartment of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (Deemed University), Porur, Chennai, 600116, Tamil Nadu, India.ORCID 0009-0009-2739-2730
Varshaa RavichandranDepartment of Biomedical Sciences, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (Deemed University), Porur, Chennai, 600116, Tamil Nadu, India.ORCID 0009-0007-9474-544X
Solomon F D PaulDepartment of Human Genetics, Head, Faculty of Clinical Research, Sri Ramachandra Institute of Higher Education and Research (Deemed University), Porur, Chennai, 600116, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Colorectal cancer has become the leading cause of death worldwide, and it is the second most common cancer in women and the third most common cancer in men. Accumulating evidence suggests that genetic and epigenetic factors play a key role in the development of colorectal cancer. Cancer Stem Cells (CSC) play an important role in the suppression or development of cancer in various conditions. In recent years, non-coding RNAs (ncRNA) have been the focus, and the association of CSC and non-coding RNA has played a crucial role in the development of human cancers. These non-coding RNAs are known to be expressed in many cancers. Studies have suggested that ncRNAs are dysregulated in colorectal cancer cells, and different factors, like Wnt and Notch, are involved in this dysregulation. ncRNAs play a significant role in cancer initiation, migration, and resistance to therapies. Moreover, long noncoding RNAs are known to regulate tumor suppressor genes or oncogenes. Targeting different ncRNAs like miRNA, circular RNA, long noncoding RNAs, and small interfering RNA may provide efficient, targeted therapeutic strategies for colon cancer treatment. This review aims to briefly discuss the latest findings on the role of noncoding RNAs in the prognosis and diagnosis of colon cancer.

Indexed as

Biomarkers, TumorColorectal NeoplasmsRNA, UntranslatedGene Expression Regulation, NeoplasticHumansMicroRNAsNeoplastic Stem CellsPrognosisRNA, Long NoncodingBiomarkers, TumorMicroRNAsRNA, Long NoncodingRNA, Untranslatedcancer stem cellcarcinogenesisColorectal cancerlong noncoding RNAncRNAsnoncoding RNAs

Identifiers

PMID39601167

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.