ReviewThe Journal of investigative dermatology2025
Practical Guide for Implementing Cryogenic Electron Microscopy Structure Determination in Dermatology Research.
Review in The Journal of investigative dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
4 authors.
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Abstract
Cryogenic electron microscopy (cryo-EM) and cryogenic electron tomography allow determination of structures of biological macromolecules in their native state in solution at atomic or near-atomic resolution. Recent advances in cryo-EM, that is, the "resolution revolution," and the establishment of national centers for cryo-EM data collection have remarkably expanded its applicability to practically all areas of health-related research. In this methods review, we highlighted the basics of single-particle cryo-EM and its application in the research of macromolecules and macromolecular complexes related to dermatology. We further illustrated a few examples of how this approach can be incorporated into drug development and study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.