Evidence map›Paper›PMID 39601948›Full record

ArticleMarine biotechnology (New York, N.Y.)2024

Identification of Key Genes Correlated with Economic Trait Superiorities and Their SNP Screening Through Transcriptome Comparisons, WGCNA and Pearson Correlation Coefficient in the Sea Cucumber Apostichopus Japonicus.

Jingxian Sun, Haolin Wang, Yaoyao Zhan, Tanjun Zhao, Chengda Li, Cao Cheng, Zengdong Wang, Ange Zou, Yaqing Chang

Abstract read
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In one paragraph

Article in Marine biotechnology (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingxian Sun *Key Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China.
Haolin Wang *Key Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China.
Yaoyao ZhanKey Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China. zyydlou@hotmail.com.
Tanjun ZhaoKey Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China.
Chengda LiKey Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China.
Cao ChengShandong Anyuan Seed Industry Technology Co., Ltd, Yantai, 265617, Shandong, P. R. China.
Zengdong WangShandong Anyuan Seed Industry Technology Co., Ltd, Yantai, 265617, Shandong, P. R. China.
Ange ZouShandong Anyuan Seed Industry Technology Co., Ltd, Yantai, 265617, Shandong, P. R. China.
Yaqing ChangKey Laboratory of Mariculture & Stock Enhancement in North China's Sea, Ministry of Agriculture and Rural Affairs, Dalian Ocean University, Dalian, 116023, Liaoning, P. R. China. yqkeylab@hotmail.com.

Funding

National Natural Science Foundation of China No. 32072977National Natural Science Foundation of China No. 32273117
6 · The paper itself

Abstract

Variation in morphology-driven economic traits is a common issue hindering the development of the sea cucumber aquaculture industry. In this study, transcriptome comparisons, weighted gene correlation network analysis (WGCNA) and Pearson correlation coefficient (PCC) were first employed to identify key genes correlated with morphological variation in the sea cucumber Apostichopus japonicus, after which the relationship between identified key genes (relative expression and genotype) and economic trait phenotypes was investigated to screen potential biomarker targets for molecular-assisted breeding. The results showed that three genes (putative ficolin-2, fibrinogen c domain-containing protein 1, and angiopoietin-4) were closely associated with economic trait superiorities. Two single nucleotide polymorphisms (SNPs) were identified in the putative ficolin-2 gene as having a strong correlation with body weight and papilla number. The findings from this study will enrich breeding biomarker resources and benefit the development of molecular-assisted breeding techniques in sea cucumber aquaculture.

Indexed as

AquaculturePolymorphism, Single NucleotideStichopusTranscriptomeAnimalsBody WeightBreedingFicolinsGene Expression ProfilingGene Regulatory NetworksGenotypeLectinsPhenotypeSea CucumbersFicolinsLectinsApostichopus japonicusEconomic trait superiorityPearson correlation coefficientSNP screeningTranscriptome comparisonWeighted gene correlation network analysis

Identifiers

PMID39601948

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.