Evidence map›Paper›PMID 39604204›Full record

ArticleRenal failure2024

Triglyceride glucose index: a significant prognostic marker of heart failure in patients with chronic kidney disease.

Shijie Liu, Xuefu Chen, Qian Guo, Jingwen Dou, Jiaxin Huang, Lewen Jia

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Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Shijie LiuNephrology Department, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Xuefu ChenCardiology Department, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Qian GuoPhysical Examination Center, Central Hospital of Dalian University of Technology, Dalian, China.
Jingwen DouNephrology Department, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Jiaxin HuangNephrology Department, The First Affiliated Hospital of Dalian Medical University, Dalian, China.
Lewen JiaNephrology Department, The First Affiliated Hospital of Dalian Medical University, Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTriglycerides and glucose (TyG) index, a relatively convenient method for assessing insulin resistance, has been confirmed as an independent predictor both for chronic kidney disease (CKD) and cardiovascular disease (CVD) in previous studies. However, a few studies focus on the prognostic value of TyG index for CVD in patients diagnosed with CKD, especially in advanced CKD patients. In this study, we aim to investigate the prognostic value of TyG index for heart failure (HF) in patients with non-dialysis CKD stage 3-5. METHODS AND

resultsThis retrospective study was conducted at The First Affiliated Hospital of Dalian Medical University. Patients with non-dialysis CKD stage 3-5 between 1 January 2016 and 1 January 2023 were included in our study. The endpoints included cardiovascular death and HF-related rehospitalization. Finally, a total of 284 subjects were enrolled in our cohort. Multivariate Cox regression analysis revealed that TyG index was one of the independent risk factors both for HF-related rehospitalization and cardiovascular death in non-dialysis CKD stage 3-5 patients. Furthermore, Cox regression model showed a favorable predictive efficiency of TyG index for adverse clinical events. Multivariate logistic regression analysis revealed that TyG index was one of the positive independent predictors of HF.

conclusionsNon-dialysis CKD stage 3-5 patients with higher TyG index level experience worsening cardiovascular outcomes, and TyG index is associated with the occurrence of HF. Highlighting that TyG index may be a significant marker for assessing cardiovascular prognosis in CKD patients.

Indexed as

BiomarkersBlood GlucoseHeart FailureRenal Insufficiency, ChronicTriglyceridesAgedChinaFemaleHumansInsulin ResistanceLogistic ModelsMaleMiddle AgedPrognosisProportional Hazards ModelsRetrospective StudiesBiomarkersBlood GlucoseTriglycerideschronic kidney diseaseheart failureinsulin resistancenon-dialysisTriglycerides and glucose index

Identifiers

PMID39604204
PMCPMC11610345

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.