Evidence map›Paper›PMID 39604492›Full record

ReviewNature medicine2024

Lifestyle interventions for cardiometabolic health.

Femke Rutters, Nicolette R den Braver, Jeroen Lakerveld, Joreintje D Mackenbach, Hidde P van der Ploeg, Simon Griffin, Petra J M Elders, Joline W J Beulens

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
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  3. Effect of combined lifestyle intervention on cardiometabolic risk in cancer survivors: A systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  4. Effect of combined lifestyle intervention on cardiometabolic risk in cancer survivors: A systematic review and meta-analysis of randomized controlled trials.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
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  20. Bioactive Potential ofPlants (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Femke RuttersDepartment of Epidemiology & Data Science, Amsterdam UMC, location Vrije Universiteit, Amsterdam, the Netherlands.
Nicolette R den BraverDepartment of Epidemiology & Data Science, Amsterdam UMC, location Vrije Universiteit, Amsterdam, the Netherlands.
Jeroen LakerveldDepartment of Epidemiology & Data Science, Amsterdam UMC, location Vrije Universiteit, Amsterdam, the Netherlands.
Joreintje D MackenbachDepartment of Epidemiology & Data Science, Amsterdam UMC, location Vrije Universiteit, Amsterdam, the Netherlands.
Hidde P van der PloegAmsterdam Public Health research institute, Amsterdam UMC, Amsterdam, the Netherlands.ORCID 0000-0002-3719-5249
Simon GriffinDepartment of Public Health and Primary Care, School of Clinical Medicine, University of Cambridge, Cambridge, UK.ORCID 0000-0002-2157-4797
Petra J M EldersAmsterdam Public Health research institute, Amsterdam UMC, Amsterdam, the Netherlands.
Joline W J BeulensDepartment of Epidemiology & Data Science, Amsterdam UMC, location Vrije Universiteit, Amsterdam, the Netherlands. j.beulens@amsterdamumc.nl.ORCID 0000-0002-4181-0937

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Unhealthy lifestyle behaviors such as poor diets and physical inactivity account for most of the cardiometabolic disease (CMD) burden, including type 2 diabetes and cardiovascular diseases. Much of this burden is mediated by the effects of unhealthy lifestyle behaviors on overweight and obesity, and disproportionally impacts certain population groups-including those from disadvantaged socioeconomic backgrounds. Combined lifestyle interventions (CLIs), which target multiple behaviors, have the potential to prevent CMD, but their implementation, reach and effectiveness in routine practice are often limited. Considering the increasing availability of effective but expensive pharmaceutical options for weight loss, we review the short-term and long-term benefits and cost-effectiveness of CLIs on overweight, obesity and associated CMDs, in controlled studies and in routine care. Against the backdrop of changing living environments, we discuss the effective components of CLIs and the many challenges associated with implementing them. Finally, we outline future directions for research and implications for policy and practice to improve lifestyle behaviors and cardiometabolic health at the population level.

Indexed as

Cardiovascular DiseasesLife StyleCost-Benefit AnalysisDiabetes Mellitus, Type 2ExerciseHumansObesityOverweight

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.