Evidence map›Paper›PMID 39604734›Full record

SynthesisNature2024

Study design features increase replicability in brain-wide association studies.

Kaidi Kang, Jakob Seidlitz, Richard A I Bethlehem, Jiangmei Xiong, Megan T Jones, Kahini Mehta, Arielle S Keller, Ran Tao, Anita Randolph, Bart Larsen and 10 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed.

  1. Trial
  2. The role of impaired mitochondrial function in neurological manifestations of mitochondrial diseases.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
    Review
  3. New waves in psychiatric neuroimaging.Nature neuroscience · 2026
    Article
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  9. Review
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  14. Neural signatures of human psychological resilience driven by acute stress.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  15. Article
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Kaidi KangDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA. kaidi.kang@vanderbilt.edu.ORCID 0000-0003-0922-5727
Jakob SeidlitzDepartment of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0002-8164-7476
Richard A I BethlehemDepartment of Psychology, University of Cambridge, Cambridge, UK.ORCID 0000-0002-0714-0685
Jiangmei XiongDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Megan T JonesDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0001-7999-7031
Kahini MehtaDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.
Arielle S KellerDepartment of Psychological Sciences, University of Connecticut, Mansfield, CT, USA.ORCID 0000-0003-4708-1672
Ran TaoDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Anita RandolphDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Bart LarsenDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Brenden Tervo-ClemmensMasonic Institute for the Developing Brain, University of Minnesota, Minneapolis, MN, USA.
Eric FeczkoDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Oscar Miranda DominguezDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Steven M NelsonDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.
Lifespan Brain Chart Consortium
Jonathan SchildcroutDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Damien A FairDepartment of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA.ORCID 0000-0001-8602-393X
Theodore D SatterthwaiteDepartment of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0001-7072-9399
Aaron Alexander-Bloch *Department of Child and Adolescent Psychiatry and Behavioral Sciences, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.ORCID 0000-0001-6554-1893
Simon Vandekar *Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA. simon.vandekar@vumc.org.ORCID 0000-0002-7457-9073

Funding

Healthy Brain and Child Development National Consortium Data Coordinating CenterU24DA055330 · NIDA · WASHINGTON UNIVERSITY · PI ANDERS M DALE, Damien A Fair · 2021 to 2026
$34.6M
ABCD-USA Consortium: Research ProjectU01DA041148 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI Damien A Fair, Rebekah S Huber · 2015 to 2026
$22.3M
Identification of outcome-based sub-populations using deep phenotyping and precision functional mapping across ADHD and ASDR01MH096773 · NIMH · UNIVERSITY OF MINNESOTA · PI DOSENBACH, NICO, FAIR, DAMIEN A · 2012 to 2024
$9.4M
Longitudinal Mapping of Network Development Underlying Executive Dysfunction in AdolescenceR01MH113550 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Danielle Smith Bassett, Theodore Satterthwaite · 2018 to 2026
$6.9M
Outcome Dependent Sampling Studies of Longitudinal Data: Design and AnalysisR01HL094786 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jonathan Scott Schildcrout · 2009 to 2026
$6.1M
Personalized Functional Network Modeling to Characterize and Predict Psychopathology in YouthR01EB022573 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Yong Fan, Theodore Satterthwaite · 2016 to 2026
$6.0M
Inter-modal Coupling Image AnalyticsR01MH112847 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI Theodore Satterthwaite, Russell Takeshi Shinohara · 2017 to 2026
$5.9M
Precision mapping of individualized executive networks in youthR37MH125829 · NIMH · UNIVERSITY OF MINNESOTA · PI Damien A Fair, Theodore Satterthwaite · 2021 to 2026
$4.7M
The Genetics of Personalized Functional MRI NetworksR01MH132934 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$4.2M
Brain trajectories in ADHDR01MH115357 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI FAIR, DAMIEN A, NIGG, JOEL T · 2017 to 2021
$3.8M
Reproducible imaging-based brain growth charts for psychiatryR01MH120482 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI MILHAM, MICHAEL PETER, SATTERTHWAITE, THEODORE · 2019 to 2023
$3.5M
Precision brain charts for imaging-genomics of schizophrenia and the psychosis spectrumR01MH133843 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$3.2M
NHLBI NIH HHS R01 HL094786NIBIB NIH HHS R01 EB022573NIDA NIH HHS K23 DA057486NIDA NIH HHS U01 DA041148NIDA NIH HHS U24 DA055330NIMH NIH HHS R00 MH127293NIMH NIH HHS R01 MH096773NIMH NIH HHS R01 MH112847NIMH NIH HHS R01 MH113550NIMH NIH HHS R01 MH115357NIMH NIH HHS R01 MH120482NIMH NIH HHS R01 MH123563NIMH NIH HHS R01 MH132934NIMH NIH HHS R01 MH133843NIMH NIH HHS R37 MH125829
6 · The paper itself

Abstract

Brain-wide association studies (BWAS) are a fundamental tool in discovering brain-behaviour associations

Indexed as

BrainMagnetic Resonance ImagingResearch DesignAdolescentAdultAgedAged, 80 and overAge FactorsAlzheimer DiseaseCognitionCross-Sectional StudiesFemaleGenome-Wide Association StudyHumansLongitudinal StudiesMale

Identifiers

PMID39604734
PMCPMC11655360

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.