Evidence map›Paper›PMID 39605508›Full record

ArticlebioRxiv : the preprint server for biology2024

CD73 restrains mutant β-catenin oncogenic activity in endometrial carcinomas.

Rebecca M Hirsch, Sunthoshini Premsankar, Katherine C Kurnit, Lilly F Chiou, Emily M Rabjohns, Hannah N Lee, Russell R Broaddus, Cyrus Vaziri, Jessica L Bowser

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Rebecca M HirschDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.ORCID 0000-0003-2363-5896
Sunthoshini PremsankarDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Katherine C KurnitDepartment of Obstetrics and Gynecology, University of Chicago, Chicago, IL, USA.
Lilly F ChiouDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Emily M RabjohnsDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Hannah N LeeDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Russell R BroaddusDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Cyrus VaziriDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.
Jessica L BowserDepartment of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA.

Funding

Targeting the PI3K Signaling Pathway in Endometrial CarcinomaP50CA098258 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI YUAN, YING · 2003 to 2020
$32.0M
NRSA in GeneticsT32GM135128 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Daniel J McKay, JEFF J. SEKELSKY · 2020 to 2026
$5.1M
Enhancement Training for the Next Generation of Translational Ph.D. ScientistsT32GM122741 · NIGMS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WOLBERG, ALISA S., YEH, JEN JEN · 2018 to 2022
$898k
NCI NIH HHS P50 CA098258NIGMS NIH HHS T32 GM122741NIGMS NIH HHS T32 GM135128
6 · The paper itself

Abstract

Missense mutations in exon 3 of

Indexed as

adenosineCD73cell adhesionsCTNNB1 mutationendometrial canceroncogeneβ-catenin

Identifiers

PMID39605508
PMCPMC11601622

What Socratic holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.