ArticleBrain communications2024
Brain age gap, dementia risk factors and cognition in middle age.
Article in Brain communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Elevated BrainAGE precedes cognitive impairment and improves prediction of future cognitive decline.medRxiv : the preprint server for health sciences · 2026Article
- ORANGE: a machine learning approach for modeling tissue-specific aging from transcriptomic data.Briefings in bioinformatics · 2026Article
- Brain Age in Adult Patients With Early-Treated Phenylketonuria.Journal of inherited metabolic disease · 2026Article
- Multimodal MRI radiomics and deep learning for brain age prediction: age-corrected brain age gap analysis in patients with insomnia.Biomedical engineering online · 2026Article
- Abdominal CT-derived metabolic phenotypes are associated with the MRI-derived brain age gap in women.Frontiers in aging neuroscience · 2026Article
- Dynamic Brain Age Modeling Identifies Network-Specific Cognitive Deficits in Schizophrenia.Research square · 2025Article
- Functional Brain Age Acceleration from Dynamic and Static Connectivity Predicts Working Memory and Attention Deficits in Schizophrenia.medRxiv : the preprint server for health sciences · 2025Article
- Association between shift work and brain age gap: a neuroimaging study using MRI-based brain age prediction algorithms.Frontiers in aging neuroscience · 2025Article
- Contributions of lifestyle, education, and cardiovascular risk factors to the brain age gap.Aging brain · 2025Article
- Psychosocial behavioral phenotypes of racially/ethnically minoritized older adults enrolled in HABS-HD differ on neuroimaging measures of brain age gap, hippocampal volume, and cortical thickness.Alzheimer's & dementia (New York, N. Y.)Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Brain Age Gap has been associated with dementia in old age. Less is known relating brain age gap to dementia risk-factors or cognitive performance in middle-age. Cognitively healthy, middle-aged subjects from PREVENT-Dementia had comprehensive neuropsychological, neuroimaging and genetic assessments. Brain Ages were predicted from T1-weighted 3T MRI scans. Cognition was assessed using the COGNITO computerized test battery. 552 middle-aged participants (median [interquartile range] age 52.8 [8.7] years, 60.0% female) had baseline data, of whom 95 had amyloid PET data. Brain age gap in middle-age was associated with hypertension (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.