Evidence map›Paper›PMID 39606246›Full record

ReviewFrontiers in immunology2024

Ion channels in acinar cells in acute pancreatitis: crosstalk of calcium, iron, and copper signals.

Hanli Wang, Jianhua Gao, Lingling Wen, Kejun Huang, Huixian Liu, Linsheng Zeng, Zhongyi Zeng, Yuxiang Liu, Zhizhun Mo

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hanli Wang *Emergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Jianhua Gao *Emergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Lingling Wen *Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Kejun HuangEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Huixian LiuEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Linsheng ZengEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Zhongyi ZengEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Yuxiang LiuEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.
Zhizhun MoEmergency Department, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, Guangdong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The initial stages of acute pancreatitis (AP) are characterized by a significant event - acinar ductal metaplasia (ADM). This process is a crucial feature of both acute and chronic pancreatitis, serving as the first step in the development of pancreatic cancer. Ion channels are integral transmembrane proteins that play a pivotal role in numerous biological processes by modulating ion flux. In many diseases, the expression and activity of ion channels are often dysregulated. Metal ions, including calcium ions (Ca

Indexed as

Acinar CellsCalciumCopperIon ChannelsIronPancreatitisAcute DiseaseAnimalsCalcium SignalingHumansSignal TransductionCalciumCopperIon ChannelsIronacinar cellsacute pancreatitisCa2+Cu2+Fe2+ion channels

Identifiers

PMID39606246
PMCPMC11599217

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.