Evidence map›Paper›PMID 39607441›Full record

ArticleArchives of gynecology and obstetrics2024

Evaluation of postpartum dysglycemia by serum glycosylated hemoglobin in patients with gestational diabetes mellitus: a national data analysis.

Nadav Cohen, Yoel Toledano, May Shafir, Ofer Lavie, Ariel Zilberlicht

Abstract read
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In one paragraph

Article in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nadav Cohen *Department of Obstetrics and Gynecology, Rappaport Faculty of Medicine, Lady Davis Carmel Medical Center, Technion University, 7 Michal Street, 34361, Haifa, Israel. nadavco@clalit.org.il.ORCID 0000-0001-7733-5026
Yoel Toledano *Division of Maternal Fetal Medicine, Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel.
May ShafirDepartment of Obstetrics and Gynecology, Rappaport Faculty of Medicine, Lady Davis Carmel Medical Center, Technion University, 7 Michal Street, 34361, Haifa, Israel.
Ofer LavieDepartment of Obstetrics and Gynecology, Rappaport Faculty of Medicine, Lady Davis Carmel Medical Center, Technion University, 7 Michal Street, 34361, Haifa, Israel.
Ariel ZilberlichtDepartment of Obstetrics and Gynecology, Rappaport Faculty of Medicine, Lady Davis Carmel Medical Center, Technion University, 7 Michal Street, 34361, Haifa, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the postpartum sensitivity and accuracy of serum HbA1c levels, compared to the gold standard of 75-g Oral Glucose Tolerance Test (OGTT), for diagnosis of dysglycemia in patients with a history of gestational diabetes mellitus (GDM).

methodsA nationwide retrospective analysis of individuals with a history of GDM and with records of both postpartum 2 h-OGTT and serum HbA1c measured anytime between delivery until 12 months post-delivery. Results were stratified into 3 different intervals: 0-3 months, 3-12 months, and > 12 months after delivery, according to the timing of both OGTT and HbA1c performance.

resultsBetween January 1st, 2015, until December 31st, 2021, a total of 55,119 individuals were screened, and 9,118 were diagnosed with GDM. Overall, 677 of the 9,118 individuals with GDM had laboratory results of both serum HbA1c levels and 2 h 75-gm-OGTT values after delivery. The overall Pearson correlation coefficient between HbA1c and 2 h-OGTT was 0.21 (P < 0.0001). However, when the OGTT results were stratified into 2 h-glucose values ≥ 200 mg/dL, a ROC curve yielded an Area Under the Curve (AUC) of 91.4% [95% CI: 83.9%-98.9%], with HbA1c levels of 5.7% yielding 80.0% sensitivity and 80.8% specificity (95% CI: 44.39-97.48%).

conclusionsIn patients with a recent diagnosis of GDM, serum HbA1c may be used as an auxiliary tool for postpartum diagnosis of dysglycemia.

Indexed as

Diabetes, GestationalGlucose Tolerance TestGlycated HemoglobinPostpartum PeriodSensitivity and SpecificityAdultBlood GlucoseFemaleHumansPregnancyRetrospective StudiesROC CurveBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human2h-75-gm OGTTDiabetes mellitusDysglycemiaGestational diabetes mellitusGlycated hemoglobinScreening

Identifiers

PMID39607441

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.