Evidence map›Paper›PMID 39607925›Full record

ArticleScience (New York, N.Y.)2024

Suppression of neurons in circumventricular organs enables months-long survival without water in thirteen-lined ground squirrels.

Madeleine S Junkins, Ni Y Feng, Dana K Merriman, Sviatoslav N Bagriantsev, Elena O Gracheva

Abstract read
In one paragraph

Article in Science (New York, N.Y.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Endothelial gateways for brain lipid uptake and metabolism.The Journal of clinical investigation · 2025
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madeleine S JunkinsDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9529-2250
Ni Y FengDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0001-9447-5944
Dana K MerrimanDepartment of Biology, University of Wisconsin-Oshkosh, Oshkosh, WI, USA.ORCID 0000-0003-2780-0772
Sviatoslav N BagriantsevDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-6661-3403
Elena O GrachevaDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, CT, USA.ORCID 0000-0002-0846-3427

Funding

Molecular and cellular basis of reversible hypothermiaR01NS126271 · NINDS · YALE UNIVERSITY · PI Elena Gracheva · 2023 to 2026
$2.0M
Molecular mechanisms of somatosensory adaptation to prolonged hypothermiaR01NS132868 · NINDS · YALE UNIVERSITY · PI Sviatoslav Bagriantsev, Elena Gracheva · 2024 to 2026
$1.6M
NINDS NIH HHS R01 NS126271NINDS NIH HHS R01 NS132868
6 · The paper itself

Abstract

Water deprivation is a life-threatening condition that engages a protective physiological response to couple osmolyte retention with potentiation of thirst. This response, typical for most mammals, safeguards against short-term water deprivation but fails in the long term. Thirteen-lined ground squirrels (

Indexed as

Circumventricular OrgansHibernationNeuronsSciuridaeThirstWater DeprivationAnimalsFemaleHomeostasisMaleSeasons

Identifiers

PMID39607925
PMCPMC11853976

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.