ArticleRenal failure2024
Assessing the predictive power of nutritional indices on all-cause and cardiovascular mortality in hemodialysis patients: a longitudinal study.
Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association between controlling nutritional status score and the prognosis of patients with acute myocardial infarction: a systematic review and meta-analysis.Frontiers in nutrition · 2024Pooled it
- Prognostic impact of severe malnutrition in dialysis patients who underwent transcatheter aortic valve replacement.Cardiovascular intervention and therapeutics · 2026Article
- Association between prognostic nutritional index and clinical outcomes in patients with pyogenic liver abscess: a retrospective multicenter study.BMC infectious diseases · 2026Article
- Geriatric Nutritional Risk Index and risks of all-cause, cardiovascular, and diabetes-related mortality in adults with obesity: A nationally representative cohort study.American heart journal plus : cardiology research and practice · 2026Article
- Association between microinflammatory state and cardiac valvular calcification in patients undergoing maintenance hemodialysis: a single-centre observational study.BMC nephrology · 2026Observational
- A Cross-Sectional Pilot Study of Probable Sarcopenia in Hemodialysis Patients.Life (Basel, Switzerland) · 2026Article
- Longitudinal trajectories of nutrition-related biomarkers and mortality risk in maintenance hemodialysis patients: a joint modeling analysis.Frontiers in nutrition · 2026Article
- Geriatric nutritional risk Index predicts adverse outcomes across cardiovascular-kidney-metabolic syndrome: discovery in NHANES and external validation in CKM stage 4 patients undergoing PCI.Frontiers in cardiovascular medicine · 2026Article
- Association of Dynamic Changes in the Neutrophil-to-Lymphocyte Ratio with Mortality in Patients on Maintenance Hemodialysis: A Retrospective Cohort Study.International journal of general medicine · 2026Article
- The Prevalence of Malnutrition and Early-Stage Age-Related Macular Degeneration: Using Three Nutritional Scoring Systems.Translational vision science & technology · 2025Article
- Mortality Risk of Sarcopenia and Malnutrition in Older Patients with Type 2 Diabetes Mellitus.Nutrients · 2025Article
- Article
- The predictive value of the pre-PCI prognostic nutritional index combined with the geriatric nutritional risk index for one-year outcomes in patients with chronic total occlusion.Frontiers in nutrition · 2025Article
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14 authors.
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Abstract
background and hypothesisThe prognostic value of nutritional scoring tools in assessing the relationship between nutritional status and prognosis in hemodialysis patients is unclear. This multicenter retrospective cohort study compared the Prognostic Nutritional Index (PNI), Controlling Nutritional Status scores (CONUT), and Geriatric Nutritional Risk Index (GNRI) for predictive accuracy of all-cause and cardiovascular mortality, especially the impact of dynamic changes over time on prognosis.
methodsHemodialysis patients from four hospitals were included. Laboratory data and nutrition scores were collected at the initiation of dialysis, and at 6th, 12th, and 18th months after dialysis initiation. A joint model analyzed the relationship between dynamic nutritional scores and prognosis. Predictive values were assessed using the area under the curve (AUC).
resultsThe study included 863 patients with a median follow-up of 37 months. During the follow-up, 23.8% of patients died, with 14% attributed to cardiovascular causes. Malnourished patients demonstrated higher risks for all-cause and cardiovascular mortality. Dynamic changes in PNI and GNRI scores were significantly associated with reduced all-cause and cardiovascular mortality risks. Precisely, longitudinal increases in PNI and GNRI scores corresponded to a 4% and 3% reduction in all-cause (PNI: HR, 0.96; 95% CI, 0.95-0.98; GNRI: HR, 0.97; 95% CI, 0.96-0.98) and cardiovascular mortality risk (PNI: HR, 0.96; 95% CI, 0.94-0.98; GNRI: HR, 0.97; 95% CI, 0.95-0.98) respectively, with longer dialysis duration. Changes in CONUT scores were not significantly associated with either all-cause or cardiovascular mortality. The AUCs of the three joint models indicated that the GNRI score (0.893) possessed higher predictive accuracy for all-cause mortality compared to PNI (0.832) and CONUT (0.852). Similar trends were observed for cardiovascular mortality.
conclusionNutritional scores and their dynamic changes are intimately associated with mortality risk in hemodialysis patients. Compared to PNI and CONUT, the baseline GNRI and its post-dialysis variations demonstrate a superior predictive capability for all-cause and cardiovascular mortality in these patients.
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