Evidence map›Paper›PMID 39609232›Full record

ReviewSurgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery2025

Assessment and medical management of weight regain after adolescent metabolic and bariatric surgery: a narrative review.

Alaina P Vidmar, Courtney E Batt, Jaime M Moore

Abstract readReview
In one paragraph

Review in Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Beyond surgery: a multimodal framework for a pediatric metabolic and bariatric surgery program in a safety-net children's hospital.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alaina P VidmarDivision of Pediatric Endocrinology, Diabetes, and Metabolism, Children's Hospital Los Angeles, University of Southern California Keck School of Medicine, Los Angeles, California.
Courtney E BattDivision of Academic Pediatrics and Adolescent Medicine, University Hospitals Rainbow Babies & Children's Hospital, Cleveland, Ohio.
Jaime M MooreDepartment of Pediatrics Section of Nutrition, University of Colorado School of Medicine, Aurora, Colorado. Electronic address: jaime.moore@cuanschutz.edu.

Funding

PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Paul S. Maclean · 1995 to 2026
$32.6M
Physiologic response to bariatric surgery and the impact of adjunct semaglutide - in adolescents (the PRESSURE trial)K23HL163480 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI Jaime M. Moore · 2023 to 2026
$745k
Impact of Meal Timing on Glycemic Profiles in Adolescents with Type 2 DiabetesK23DK134801 · NIDDK · CHILDREN'S HOSPITAL OF LOS ANGELES · PI Alaina P Vidmar · 2023 to 2026
$674k
NHLBI NIH HHS K23 HL163480NIDDK NIH HHS K23 DK134801NIDDK NIH HHS P30 DK048520
6 · The paper itself

Abstract

Metabolic and bariatric surgery (MBS) in adolescents results in durable treatment of severe obesity and related complications for most. However, substantial weight regain can undermine long-term health benefits. There is no evidence-based standard of care for the medical management of weight regain after MBS in pediatrics or adults. This narrative review summarizes current pediatric evidence pertaining to the assessment and medical management of post-MBS weight regain, identifies gaps, and offers recommendations. A PubMed search was conducted through March 2024 and focused on adolescents after sleeve gastrectomy or Roux-en-Y gastric bypass. Domains included nutrition, activity, mental health, antiobesity medications, type 2 diabetes, hypothalamic obesity, and transition of care. In total, 600 articles were screened and 61 were included in this review. Recent consensus definitions for post-MBS weight regain have been established for adults but have not been validated in pediatrics. Limited, high-quality evidence was identified in the nutrition domain, where targets that may mitigate weight regain include adequate protein intake (≥60 g/d), absence of loss-of-control eating, and micronutrient sufficiency. Emerging data for post-MBS antiobesity medications in adults with/without diabetes and in adolescents with persistent obesity are promising. Large gaps include post-MBS interventions focused on physical activity and mental health. The overall quality of pediatric-specific evidence for the assessment and medical management of post-MBS weight regain is low. A standard definition of weight regain associated with health outcomes in pediatrics would be valuable. Clarifying risk and protective factors for weight regain can guide more precise risk stratification and treatment.

Indexed as

Bariatric SurgeryPediatric ObesityWeight GainAdolescentAnti-Obesity AgentsHumansObesity, MorbidAnti-Obesity AgentsAntiobesity medicationsPediatric bariatric surgeryRoux-en-Y gastric bypassSleeve gastrectomyType 2 diabetesWeight regain

Identifiers

PMID39609232
PMCPMC11729465

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.