Evidence mapPaperPMID 39609355Full record

ReviewTargeted oncology2025

Unveiling the Digital Evolution of Molecular Tumor Boards.

Sebastian Lutz, Alicia D'Angelo, Sonja Hammerl, Maximilian Schmutz, Rainer Claus, Nina M Fischer, Frank Kramer, Zaynab Hammoud

Abstract readReview
In one paragraph

Review in Targeted oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. AI assistance in tumor multidisciplinary teams.ESMO real world data and digital oncology · 2026
    Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sebastian LutzIT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany. sebastian.lutz@uni-a.de.ORCID http://orcid.org/0009-0003-2593-191X
Alicia D'AngeloIT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany.
Sonja HammerlIT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany.
Maximilian SchmutzInstitute of Digital Medicine (IDM), Medical Faculty, University of Augsburg, Augsburg, Germany.ORCID http://orcid.org/0000-0002-7453-7260
Rainer ClausHematology and Oncology, Faculty of Medicine, University of Augsburg, Augsburg, Germany.ORCID http://orcid.org/0000-0003-2617-8766
Nina M FischerBavarian Cancer Research Center (BZKF), Augsburg, Germany.ORCID http://orcid.org/0009-0008-7016-8761
Frank KramerIT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany.ORCID http://orcid.org/0000-0002-2857-7122
Zaynab HammoudIT-Infrastructure for Translational Medical Research, University of Augsburg, Augsburg, Germany.ORCID http://orcid.org/0000-0001-5943-3941

Funding

Bundesministerium für Bildung und Forschung FKZ01ZZ2008
6 · The paper itself

Abstract

Molecular tumor boards (MTB) are interdisciplinary conferences involving various experts discussing patients with advanced tumors, to derive individualized treatment suggestions based on molecular variants. These discussions involve using heterogeneous internal data, such as patient clinical data, but also external resources such as knowledge databases for annotations and search for relevant clinical studies. This imposes a certain level of complexity that requires huge effort to homogenize the data and use it in a speedy manner to reach the needed treatment. For this purpose, most institutions involving an MTB are heading toward automation and digitalization of the process, hence reducing manual work requiring human intervention and subsequently time in deriving personalized treatment suggestions. The tools are also used to better visualize the patient's data, which allows a refined overview for the board members. In this paper, we present the results of our thorough literature research about MTBs, their process, the most common knowledge bases, and tools used to support this decision-making process.

Indexed as

NeoplasmsPrecision MedicineHumans

Identifiers

PMID39609355
PMCPMC11762447

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.