ArticleNature immunology2025
Circulating tumor-reactive KIR
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- Spatiotemporal single-cell profiling reveals T cell clonal dynamics and phenotypic plasticity in human graft-versus-host disease.Nature immunology · 2026Article
- Circulating B cell and T cell activation states predict clinical outcomes in melanoma and reveal dynamic immune reinvigoration with checkpoint inhibitor immunotherapy.Journal for immunotherapy of cancer · 2026Article
- Vitamin B5 supports anti-PD1 response in HER2-positive gastric cancer and enhances interaction between naïve B cells and T cells.Nature communications · 2026Article
- Long-term depletion of KIR3DL01+ NK cells by adeno-associated viral-vectored antibody delivery alters chronic SIV infection.PLoS pathogens · 2026Article
- CD8Molecular therapy : the journal of the American Society of Gene Therapy · 2026Article
- scSurvival: Single-Cell Survival Analysis of Clinical Cancer Cohort Data at Cellular Resolution.Cancer discovery · 2026Article
- CD8+ Regulatory T Cells.Annual review of immunology · 2026Review
- Fusing data from CT deep learning, CT radiomics and peripheral blood immune profiles to diagnose lung cancer in a cohort of patients experiencing symptoms.EBioMedicine · 2026Article
- Antigen-experienced NK-T cells: integrating new insights and exploring therapeutic potential in cancer immunotherapy.Frontiers in immunology · 2026Review
- Neuron-reactive KIRNature communications · 2025Article
- Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
- Update of
Authors and funding
27 authors.
Benjamin Y LuDepartment of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT, USA. Benjamin.Lu@yale.edu.ORCID 0000-0001-8764-8384
Liliana E LuccaDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Wesley LewisInterdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, USA.
Jiping WangApplied Mathematics Program, Yale University, New Haven, CT, USA.
Catarina V NogueiraRepertoire Immune Medicines, Cambridge, MA, USA.
Sebastian HeerRepertoire Immune Medicines, Schlieren, Switzerland.ORCID 0000-0001-7802-8685
Violeta Rayon-EstradaRepertoire Immune Medicines, Cambridge, MA, USA.
Pierre-Paul AxisaDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0003-1446-3922
Sarah M ReevesDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, USA.
Nicholas C Buitrago-PocasangreDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-1333-4435
Giang H PhamDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Mina L KojimaDepartment of Genetics, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-3387-8608
Wei WeiDepartment of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT, USA.
Lilach AizenbudDepartment of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT, USA.
Antonietta BacchiocchiDepartment of Dermatology, Yale School of Medicine, New Haven, CT, USA.
Lin ZhangDepartment of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT, USA.
Joseph J WalewskiDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA.
Veronica ChiangDepartment of Neurosurgery, Yale School of Medicine, New Haven, CT, USA.
Kelly OlinoDepartment of Surgery, Yale School of Medicine, New Haven, CT, USA.
James CluneDepartment of Surgery, Yale School of Medicine, New Haven, CT, USA.
Ruth HalabanDepartment of Dermatology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0001-8451-1964
Yuval KlugerDepartment of Pathology, Yale School of Medicine, New Haven, CT, USA.ORCID 0000-0002-3035-071X
Anthony J CoyleRepertoire Immune Medicines, Cambridge, MA, USA.
Jan KisielowRepertoire Immune Medicines, Schlieren, Switzerland.ORCID 0000-0002-4482-5202
Franz-Josef ObermairRepertoire Immune Medicines, Schlieren, Switzerland.ORCID 0000-0002-3918-800X
Harriet M KlugerDepartment of Medicine (Medical Oncology), Yale School of Medicine, New Haven, CT, USA.
David A HaflerDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA. David.Hafler@yale.edu.ORCID 0000-0003-4664-535X
Funding
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 1985 to 2026
$85.0MRole of Negative Costimulation in Regulation of AutoimmunityP01AI039671 · NIAID · YALE UNIVERSITY · PI VIJAY K. KUCHROO · 1996 to 2026
$51.7MYale SPORE in Skin CancerP50CA121974 · NCI · YALE UNIVERSITY · PI MARCUS W BOSENBERG, Harriet M. Kluger · 2006 to 2026
$43.9MMEDICAL INFORMATICS RESEARCH TRAINING AT YALET15LM007056 · NLM · YALE UNIVERSITY · PI Mark Bender Gerstein, LUCILA OHNO-MACHADO · 1987 to 2026
$22.2MINTERDISCIPLINARY IMMUNOLOGY TRAINING PROGRAMT32AI007019 · NIAID · YALE UNIVERSITY · PI Carrie L. Lucas, David G. Schatz · 1985 to 2026
$14.4MA Catalog of Cell Types and Genomic Elements in Tissues, Organoids and DiseaseUM1HG009390 · NHGRI · BROAD INSTITUTE, INC. · PI BERNSTEIN, BRADLEY EVAN · 2017 to 2021
$11.0MYALE CANCER CENTER CALABRESI IMMUNO-ONCOLOGY TRAINING PROGRAMK12CA215110 · NCI · YALE UNIVERSITY · PI Harriet M. Kluger · 2018 to 2026
$6.1M(8) Mechanisms of autoimmune endocrine diseases in patients receiving checkpoint inhibitorsR01CA227473 · NCI · YALE UNIVERSITY · PI HEROLD, KEVAN C, KLUGER, HARRIET M. · 2018 to 2022
$3.2MYale Cancer Center Advanced Training Program for Physician-Scientists (YCC-ATPP)T32CA233414 · NCI · YALE UNIVERSITY · PI Eric P. Winer · 2019 to 2026
$3.2MImmune Therapy for Brain MetastasisR01CA269286 · NCI · YALE UNIVERSITY · PI Lucia Beatrice Jilaveanu, Harriet M. Kluger · 2023 to 2026
$2.2MHigh Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2MNCI NIH HHS K12 CA215110NCI NIH HHS P30 CA016359NCI NIH HHS P50 CA121974NCI NIH HHS R01 CA227473NCI NIH HHS R01 CA269286NCI NIH HHS T32 CA233414NHGRI NIH HHS UM1 HG009390NIAID NIH HHS P01 AI039671NIAID NIH HHS T32 AI007019NIH HHS S10 OD030363NLM NIH HHS T15 LM007056U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) K12 CA215510U.S. Department of Health & Human Services | NIH | National Cancer Institute (NCI) R01 CA121974U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01 AI22220U.S. Department of Health & Human Services | NIH | National Institute of Allergy and Infectious Diseases (NIAID) U24 AI11867
Abstract
Effective anti-tumor immunity is driven by cytotoxic CD8
Indexed as
CD8-Positive T-LymphocytesMelanomaReceptors, KIRAntigens, NeoplasmFemaleHumansT-Lymphocytes, RegulatoryTumor EscapeAntigens, NeoplasmReceptors, KIR
Identifiers
What Socratic holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.