SynthesisHypertension research : official journal of the Japanese Society of Hypertension2025
Resistance exercise has an antihypertensive effect comparable to that of aerobic exercise in hypertensive patients: a meta-analysis of randomized controlled trials.
Synthesis in Hypertension research : official journal of the Japanese Society of Hypertension, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Exercise for prevention and treatment of hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Exercise Training Across the Hypertensive Heart Disease Continuum: Clinical Evidence and Implications for Prescription.Journal of cardiovascular development and disease · 2026Review
- What is "Implementation Hypertension"? Uniting individuals, healthcare, and society around blood pressure.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Additional blood-pressure-lowering effect of exercise in adults on stable antihypertensive medication: a systematic review and meta-analysis of randomised controlled trials.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Impact of resistance training for lowering blood pressure in older adults.American journal of preventive cardiology · 2026Article
- Effects of Resistance Training on Systolic and Diastolic Blood Pressure in Hypertensive Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Optimal Exercise Modalities and Dosages for Blood Pressure Reduction in Adults With Prehypertension and Established Hypertension: A Network Meta-Analysis and Dose-Response Relationship Study.Journal of the American Heart Association · 2026Review
- Effect of exercise and physical activity on blood pressure reduction.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Review
- Global guidelines recommendations for lifestyle modifications in patients with hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- The Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Reply to the Letter to the Editor: "Should Resistance Training Also Be Considered a Mandatory Component?"Arquivos brasileiros de cardiologia · 2026Article
- Exercise in CKM syndrome progression: a stage-specific approach to cardiovascular, metabolic, and renal health.Cardiovascular diabetology · 2025Review
- The JSH Morning Hypertension Eradication Program Project.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Key highlights of the Japanese Society of Hypertension Guidelines for the management of elevated blood pressure and hypertension 2025 (JSH2025).Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
Corrections and comments
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Authors and funding
44 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hypertension increases the risk of cerebrovascular disease and death. In addition to aerobic exercise, which is currently recommended for its antihypertensive effects, recent studies have suggested that dynamic and isometric resistance exercises also have antihypertensive effects. However, the magnitude of the antihypertensive effect of such resistance exercises is not well known. To clarify the differences in these effects, we conducted an umbrella review of a meta-analysis of randomized controlled trials (RCTs). A systematic search was performed on the Ovid MEDLINE and Cochrane Library, covering the period from inception to August 1, 2023. Eligible studies were RCTs comparing the effects of exercise and non-exercise on office, home, or ambulatory blood pressure (BP) in hypertensive patients aged 18 years or older. A random effects model meta-analysis was performed to estimate the effect size across multiple studies. A sub-analysis determined outcomes by the type of exercise (aerobic exercise, dynamic resistance exercise, isometric resistance exercise, and combined exercise). Eighty-four RCTs with 5065 hypertensive patients were included in the study. All exercise significantly reduced systolic BP (SBP) and diastolic BP (DBP) compared to non-exercise (SBP:-7.52 mmHg, 95% confidence interval [CI] -8.77 to -6.27, p < 0.001; DBP: -4.36 mmHg, 95% CI - 5.15 to -3.57, p < 0.001). There were no significant differences in the magnitude of the reduction in BP between the types of exercise (p for interaction = 0.815 for SBP, p = 0.417 for DBP). These data from 84 RCTs showed that exercise intervention significantly reduced BP and that resistance exercise has a similar antihypertensive effect to aerobic exercise in hypertensive patients. This meta-analysis showed that exercise significantly reduced blood pressure in hypertensive patients. There were no significant differences in the magnitude of this reduction in BP between the types of exercise.
Indexed as
Identifiers
39609644What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.