SynthesisThe international journal of behavioral nutrition and physical activity2024
Physical activity and mental health: a systematic review and best-evidence synthesis of mediation and moderation studies.
Synthesis in The international journal of behavioral nutrition and physical activity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 148 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
148 citing papers in PubMed, 9 syntheses or guidelines pooled it.
- Associations Between Motor Competence and Mental Health in Youth: A Systematic Review and Meta-Analysis.European journal of sport science · 2026Pooled it
- The impact of sports participation on psychological health and social outcomes in children and adolescents: a systematic review and update to the "Mental Health through Sport" conceptual model.Systematic reviews · 2026Pooled it
- Domain-specific physical activity and mental health: an updated systematic review and multilevel meta-analysis in a combined sample of 3.3 million people.British journal of sports medicine · 2026Pooled it
- Effects of physical activity interventions on mental health in children and adolescents: a systematic review and meta-analysis of intervention type and baseline risk as moderators.Frontiers in psychology · 2026Pooled it
- Motivational climate in school sport and adolescent mental health: a systematic review.Frontiers in psychiatry · 2026Pooled it
- The association between accelerometer-measured physical activity and symptoms of depression and anxiety in children and adolescents: a systematic review and meta-analysis.BMC pediatrics · 2025Pooled it
- The effects of different types of leisure-time physical activity on positive mental health among adolescents: a mixed-methods systematic review and meta-analysis.The international journal of behavioral nutrition and physical activity · 2025Pooled it
- Effects of urban green exercise on mental health: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- The mediating effect of resilience and self-efficacy between physical activity and wellbeing: a meta-analytic structural equation modeling.Frontiers in psychology · 2025Pooled it
- Extended Long-Term Effects of Cognitive and Aerobic Training on Cognitive Function in Patients With Stress-Related Exhaustion Disorder: A 4.5-Year Follow-Up of a Randomized Controlled Trial.Stress and health : journal of the International Society for the Investigation of Stress · 2026Trial
- An mHealth Intervention Promoting Physical Activity to Reduce Psychological Distress Among Workers: Randomized Controlled Trial.Journal of medical Internet research · 2026Trial
- Examining the Social and Mental Health Benefits of Virtual and In-Person Physical Activity Intervention Among Postsecondary Students: Quasi-Experimental Study.JMIR mental health · 2026Trial
- Effects of wrestling training on psychological well-being, anxiety, and resilience in adolescent boys.BMC psychology · 2026Trial
- Joint Trajectories of Physical Activity and Depressive Symptoms and Incident Cardiometabolic Multimorbidity: A Multi-Cohort Study.Diabetes, obesity & metabolism · 2026Article
- Exercise Dependence and Its Health Correlates: A Cross-Sectional Survey-Based Study of Impulsivity, Depression Symptom Severity, and Exercise Duration.Health science reports · 2026Article
- Article
- Factors Associated with Smoking Status and Self-Reported Physical Activity Among Spanish Nursing Professionals: A Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2026Article
- Self-Reported Outdoor Activities and Perceived Stress During the First COVID-19 Wave: A Cross-Sectional Study in Poland and Italy.Medicina (Kaunas, Lithuania) · 2026Article
- Exercise Training Characteristics and Psycho-Bio-Chemical Outcomes in Individuals with Addictive Behaviours: A Scoping Review.Journal of functional morphology and kinesiology · 2026Review
- Motivational and Behavioural Physical Activity as Differential Correlates of Well-Being Following Mass Trauma: A Three-Group Study of Direct, Vicarious, and Non-Exposed Individuals.Stress and health : journal of the International Society for the Investigation of Stress · 2026Article
88 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile evidence consistently demonstrates that physical activity is beneficial to mental health, it remains relatively unknown how physical activity benefits mental health, and which factors influence the effect of physical activity on mental health. This understanding could vastly increase our capacity to design, recommend, and prescribe physical activity in more optimal ways. The purpose of this study was to systematically review and synthesise evidence of all mediators and moderators of the relationship between physical activity and mental health.
methodsSystematic searches of four databases (i.e., Scopus, PsycINFO, PubMed, and SPORTDiscus) identified 11,633 initial studies. Empirical studies that quantitatively assessed physical activity, or conducted a physical activity intervention, measured a mental health outcome, and tested one or more mediator or moderator of the relationship between physical activity and mental health were included. A total of 247 met the inclusion criteria; 173 studies examined mediation and 82 examined moderation.
resultsResults of the best-evidence synthesis revealed strong evidence for 12 mediators including affect, mental health and wellbeing, self-esteem, self-efficacy, physical self-worth, body image satisfaction, resilience, social support, social connection, physical health, pain, and fatigue. Moderate evidence was identified for a further 15 mediators and eight moderators.
conclusionsFindings should inform the design of future physical activity interventions to ensure optimal effects on mental health related outcomes. Additionally, if health professionals were to take these mediators and moderators into consideration when prescribing or recommending physical activity, physical activity would likely have a greater impact on population mental health.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.