Evidence map›Paper›PMID 39610030›Full record

ArticleVeterinary ophthalmology2025

Retrospective study on Encephalitozoon cuniculi infections in 118 cat and 9 dog eyes.

Sophie Hofmann-Wellenhof, Barbara Nell

Abstract read
In one paragraph

Article in Veterinary ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sophie Hofmann-WellenhofDepartment for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.ORCID https://orcid.org/0009-0009-3537-8568
Barbara NellDepartment for Companion Animals and Horses, University of Veterinary Medicine Vienna, Vienna, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aims to inform about the clinical image, diagnostic possibilities, and treatment options for cats and dogs diagnosed with ocular encephalitozoonosis. MATERIALS AND

methodsMedical records of 7 dogs and 75 cats with ocular encephalitozoonosis presented at the Clinical Unit of Ophthalmology of the University of Veterinary Medicine Vienna between 08/2006 and 02/2022 have been compiled. Diagnosis was based on the presence of cataracts and positive antibody titer against Encephalitozoon cuniculi. Patient history, details on the characteristics of the cataracts, level of antibody titers, and the treatment regimen were summarized, as are the results of histological stainings of surgical samples to determine the presence of Encephalitozoon cuniculi, as well as PCR analyses to identify its sub-strains.

resultsOur analysis of the clinical data shows that focal cortical anterior cataracts often associated with anterior uveitis and lesions in the fundus are the most prevalent manifestation of ocular encephalitozoonosis in cats and dogs.

conclusionSerological testing and PCR analysis of lens material are the most important diagnostic tools. Timely phacoemulsification with adjuvant anti-inflammatory and antiparasitic medication is the most promising therapy for Encephalitozoon cuniculi-induced cataracts.

Indexed as

Cat DiseasesDog DiseasesEncephalitozoon cuniculiEncephalitozoonosisEye Infections, FungalAnimalsCataractCatsDogsFemaleMaleRetrospective Studiescaninecataracteyefelinelensmicrosporidia

Identifiers

PMID39610030
PMCPMC12488539

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.