Evidence mapPaperPMID 39610875Full record

ArticleFrontiers in nutrition2024

Harnessing the nutraceutical and therapeutic potential of

Kalyani Gorrepati, Ram Krishna, Saurabh Singh, Dhananjay V Shirsat, P S Soumia, Vijay Mahajan

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kalyani GorrepatiICAR-Directorate of Onion and Garlic Research, Rajgurunagar, Pune, India.
Ram KrishnaICAR-Indian Institute of Vegetable Research, Varanasi, India.
Saurabh SinghInstitute of Environment and Sustainable Development, Banaras Hindu University, Varanasi, India.
Dhananjay V ShirsatICAR-Directorate of Onion and Garlic Research, Rajgurunagar, Pune, India.
P S SoumiaICAR-Directorate of Onion and Garlic Research, Rajgurunagar, Pune, India.
Vijay MahajanICAR-Directorate of Onion and Garlic Research, Rajgurunagar, Pune, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apart from the culinary usage, Alliums are known for their therapeutic potential since antiquity. Alliums contain diverse bioactive compounds such as, sulfur-containing compounds (allicin, diallyl sulfides), flavonoids, and saponins. These compounds have demonstrated a wide range of pharmacological actions, including antioxidant, anticancer, anti-inflammatory, antimicrobial, neuroprotective, cardioprotective activities and treatment of metabolic disorders such as diabetes and hyperlipidemia. Despite encouraging preclinical results, translating these findings into clinical practice remains difficult, necessitating more rigorous human trials and molecular research. One of the major constrain in enhancing the therapeutic efficacy of these bioactive compound is to develop large-scale extraction techniques besides improving their stability, solubility, and bioavailability. The current scenario urges to focus research on optimizing the bioavailability of these compounds, evaluate their synergistic effects with existing therapies, as well as their long-term safety. This perspective article provides a comprehensive overview of the therapeutic potential of

Indexed as

Alliumbioactive compoundshealth benefitsnutraceuticalstherapeutic properties

Identifiers

PMID39610875
PMCPMC11602312

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.