Evidence map›Paper›PMID 39611847›Full record

ArticlemBio2025

The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in

Alexander A Morano, Wei Xu, Francesca M Navarro, Neeta Shadija, Jeffrey D Dvorin, Hangjun Ke

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The trypanosomatid dynamin-like protein associates with glycosomes.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Detailing organelle division and segregation inbioRxiv : the preprint server for biology · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Alexander A Morano *Division of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Wei Xu *Center for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Francesca M NavarroDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.
Neeta ShadijaCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.
Jeffrey D DvorinDivision of Infectious Diseases, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID 0000-0002-5883-7271
Hangjun KeCenter for Molecular Parasitology, Department of Microbiology and Immunology, Drexel University College of Medicine, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-2006-3987

Funding

Functional investigation of a novel and essential subcellular compartment in Plasmodium falciparum transmission stage parasitesR01AI169648 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI JEFFREY D DVORIN · 2022 to 2026
$3.7M
Molecular mechanisms of schizogony in malaria parasitesR01AI145941 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI DVORIN, JEFFREY D · 2019 to 2023
$3.1M
Proton pumping and energy metabolism of the ring stage malaria parasitesR01AI184855 · NIAID · DREXEL UNIVERSITY · PI Hangjun Ke · 2024 to 2026
$1.7M
PfVP1, a battery of the malaria parasite, is critical for ring stage developmentR21AI156735 · NIAID · DREXEL UNIVERSITY · PI KE, HANGJUN · 2021 to 2022
$414k
Characterizing a novel Plasmodium cytoskeletal proteinF31AI181256 · NIAID · HARVARD MEDICAL SCHOOL · PI Francesca Maria Navarro · 2024 to 2026
$119k
Characterizing a Serine-Threonine Phosphatase Essential for Asexual Replication in Plasmodium falciparumF31AI157041 · NIAID · HARVARD MEDICAL SCHOOL · PI MORANO, ALEXANDER AENEAS · 2022 to 2024
$91k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R21 AI156735, R01AI184855NIAID NIH HHS F31 AI157041NIAID NIH HHS F31 AI181256NIAID NIH HHS R01 AI145941NIAID NIH HHS R01 AI169648NIAID NIH HHS R01 AI184855NIAID NIH HHS R21 AI156735
6 · The paper itself

Abstract

Dynamins, or dynamin-related proteins (DRPs), are large mechano-sensitive GTPases that mediate membrane dynamics or organellar fission/fusion events.

Indexed as

ApicoplastsDynaminsMitochondriaMitochondrial DynamicsPlasmodium falciparumProtozoan ProteinsErythrocytesHumansSchizontsDynaminsProtozoan Proteinsapicoplastapicoplast fissionbasal complexdynamindynamin-related proteinmalariamitochondriamitochondrial fissionPfDyn2Plasmodium falciparumresidual bodyschizogony

Identifiers

PMID39611847
PMCPMC11708027

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.