Evidence map›Paper›PMID 39612339›Full record

ArticleScience advances2024

Convergent evolution of berberine biosynthesis.

Zhichao Xu, Ya Tian, Jing Wang, Yuwei Ma, Qi Li, Yuanze Zhou, Wanran Zhang, Tingxia Liu, Lingzhe Kong, Yifan Wang and 16 more

Abstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  4. Dynamic diversification of lignan metabolism in sesame via coordinated oxygenation and glucosylation across germination.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  6. Review
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  8. Convergence and parallelism in the evolution of plant metabolism.Journal of integrative plant biology · 2026
    Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Natural novel vitamin C derivative, 2-Chinese herbal medicines · 2026
    Review
  14. Article
  15. Article
  16. Altitudinal changes induce responses inFrontiers in plant science · 2026
    Article
  17. Article
  18. Article
  19. Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Zhichao XuKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0000-0003-1753-5602
Ya TianKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0000-0001-9482-4307
Jing WangKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0000-0003-0942-5470
Yuwei MaKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Qi LiKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Yuanze ZhouDepartment of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.
Wanran ZhangKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Tingxia LiuKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
Lingzhe KongKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Yifan WangKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0009-0009-5987-6246
Ziyan XieKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Zhoujie AnKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0000-0002-1638-3179
Baojiang ZhengKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.
Yuhong ZhangCollege of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China.ORCID 0000-0003-4230-5868
Chang CaoCollege of Chemistry, Chemical Engineering and Resource Utilization, Northeast Forestry University, Harbin 150040, China.
Chengwei LiuKey Laboratory of Saline-alkali Vegetation Ecology Restoration (Northeast Forestry University), Ministry of Education, Harbin 150040, China.ORCID 0000-0003-2746-2080
Lixia TianSchool of Pharmaceutical Sciences, Guizhou University, Guiyang 550025, China.
Chengpeng FanSchool of Basic Medical Sciences, Wuhan University, Wuhan 430072, China.
Jiushi LiuKey Lab of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.ORCID 0000-0003-2678-6155
Hui YaoKey Lab of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Jingyuan SongKey Lab of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.
Baozhong DuanCollege of Pharmaceutical Science, Dali University, Dali 671003, China.
Haitao LiuKey Lab of Chinese Medicine Resources Conservation, State Administration of Traditional Chinese Medicine of the People's Republic of China, Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100193, China.ORCID 0009-0002-4342-3938
Ranran GaoKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0002-7164-0289
Wei SunKey Laboratory of Beijing for Identification and Safety Evaluation of Chinese Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.ORCID 0000-0001-5675-0466
Shilin ChenInstitute of Herbgenomics, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China.ORCID 0000-0002-0449-236X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Berberine is an effective antimicrobial and antidiabetic alkaloid, primarily extracted from divergent botanical lineages, specifically

Indexed as

BerberineBiosynthetic PathwaysCoptisEvolution, MolecularMethylationMethyltransferasesPhellodendronPhylogenyPlant ProteinsBerberineMethyltransferasesPlant Proteins

Identifiers

PMID39612339
PMCPMC11606445

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.