Evidence map›Paper›PMID 39613797›Full record

ArticleScientific reports2024

Longitudinal associations between fruit and vegetable intakes and depressive symptoms in middle-aged and older adults from four international twin cohorts.

Annabel P Matison, Anbupalam Thalamuthu, Victoria M Flood, Vibeke S Catts, Kaare Christensen, Marianne Nygaard, Nancy L Pedersen, Perminder S Sachdev, Simone Reppermund, Karen A Mather and 1 more

Abstract readTwin Study
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Annabel P MatisonCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia. a.matison@unsw.edu.au.
Anbupalam ThalamuthuCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
Victoria M FloodFaculty of Medicine and Health, The University of Sydney, Sydney, NSW, Australia.
Vibeke S CattsCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
Kaare ChristensenThe Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.
Marianne NygaardThe Danish Twin Registry, Department of Public Health, University of Southern Denmark, Odense, Denmark.
Nancy L PedersenDepartment of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.
Perminder S SachdevCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
Simone ReppermundCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
Karen A MatherCentre for Healthy Brain Ageing, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, Faculty of Medicine and Health, UNSW Sydney, Sydney, NSW, Australia.
Interplay of Genes and Environment across Multiple Studies (IGEMS) consortium

Funding

TRAJECTORIES OF MORTALITY IN CAENORHABDITIS ELEGANSP01AG008761 · NIA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI VAUPEL, JAMES W. · 1990 to 2008
$17.5M
Sex differences in the relationship between APOE and AD: Role of sexual differentiationRF1AG058068 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, LADU, MARY JO · 2017 to 2017
$3.8M
Clarifying risk and protective factors for dementia with the Interplay of Genes and Environment in Multiple Studies (IGEMS) consortiumR01AG060470 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2018 to 2022
$3.6M
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR01AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 2010 to 2014
$3.2M
SES health gradients in late life: testing models of gene-environment interplay in an international twin consortiumR01AG059329 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FINCH, BRIAN K., GATZ, MARGARET · 2018 to 2022
$2.9M
GENETIC &ENVIRONMENTAL INFLUENCES--BIOBEHAVIORAL AGINGR01AG010175 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI PEDERSEN, NANCY L · 1992 to 2006
$2.8M
Gene-Environment Interplay of Social Contexts and Aging-Related OutcomesR56AG037985 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GATZ, MARGARET, PEDERSEN, NANCY L · 2016 to 2016
$818k
NIA NIH HHS P01 AG008761NIA NIH HHS R01 AG010175NIA NIH HHS R01 AG037985NIA NIH HHS R01 AG059329NIA NIH HHS R01 AG060470NIA NIH HHS R56 AG037985NIA NIH HHS RF1 AG058068
6 · The paper itself

Abstract

Beneficial associations between higher fruit and vegetable intakes and risk of depression appear to exist but few studies have focused on adults aged 45 + years and the potential that associations are due to residual confounding has not been tested. This longitudinal study of twins (n = 3483, age 45-90 years) from Australia, Denmark, Sweden and USA, assessed the associations between baseline fruit/vegetable intake and depressive symptoms over 5-11 years using linear mixed effects models. Intakes from food frequency questionnaires were trichotomized. Depressive symptoms were assessed using validated measures. The co-twin method was used to examine familial confounding. Compared with low intakes, both high fruit and high vegetable intakes were associated with lower depressive symptoms (fruit: β -.007 [95%CI - .014, < - .001], p = .040; vegetables: β - .006 [95%CI -.011, -.002], p = .002); whereas only moderate vegetable intakes, were associated with lower depressive symptoms (vegetables: β - .005 [95%CI - .009, - .001], p = .014). No familial confounding was found for vegetables, while the results for fruit were inconclusive, likely due to smaller sample size and the marginal significance of the main result. Higher fruit and vegetable intakes may protect against depressive symptoms, presenting another argument for increasing intakes in adults aged 45 + years.

Indexed as

DepressionFruitVegetablesAgedAged, 80 and overAustraliaDenmarkDietFemaleHumansLongitudinal StudiesMaleMiddle AgedSwedenUnited StatesDepressive symptomsFruitLongitudinal studyTwin studyVegetables

Identifiers

PMID39613797
PMCPMC11607319

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.