Evidence map›Paper›PMID 39613833›Full record

ArticleScientific reports2024

Reduced antimicrobial use in weaned pigs through an intervention program supporting veterinarians' adherence to the clinical practice Streptococcus suis guideline.

Isaura Y A Wayop, Panagiotis Mallioris, Emely de Vet, Menno van Woerkom, Pim Sanders, Jaap A Wagenaar, David C Speksnijder

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Isaura Y A WayopDivision of Infectious Diseases and Immunology, Department Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, Utrecht, 3584 CL, The Netherlands.
Panagiotis MalliorisDivision of Infectious Diseases and Immunology, Department Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, Utrecht, 3584 CL, The Netherlands.
Emely de VetTilburg School of Humanities and Digital Sciences, University College Tilburg, PO Box 90153, Tilburg, 5000 LE, The Netherlands.
Menno van WoerkomThe Dutch Institute for Rational Use of Medicine (IVM), Churchilllaan 11, Utrecht, 3527 GV, The Netherlands.
Pim SandersThe Netherlands Veterinary Medicines Institute (SDa), Utrecht, The Netherlands.
Jaap A WagenaarDivision of Infectious Diseases and Immunology, Department Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, Utrecht, 3584 CL, The Netherlands.
David C SpeksnijderDivision of Infectious Diseases and Immunology, Department Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, Utrecht, 3584 CL, The Netherlands. d.c.speksnijder@uu.nl.

Funding

ZonMw 541002005
6 · The paper itself

Abstract

Veterinary guidelines have been published in the Netherlands to promote antimicrobial stewardship. An evidence-based intervention program using Implementation Mapping and performance indicators was developed to enhance veterinarians' adherence to the veterinary guideline "Streptococcus suis in weaned pigs". The present study evaluates the effect of this eight-month intervention program in a multicenter, pragmatic, stepped-wedge cluster design trial. Of the 49 veterinarians that participated, 33 provided data from 125 S. suis problem farms. A baseline measurement (M0) before the intervention program, and two measurements during (M1) and partly after (M2) the intervention program were conducted. A significant reduction in farm-level antimicrobial use of 25% in M1 and 49% in M2 was achieved compared to M0. For the performance indicators at veterinarian level, a significant reduction (- 36%) was found for antimicrobial prescription in M2, a significant increase occurred in argumentation for 2nd choice antimicrobials (M2) and the usage of bacteriological examination (M1). Two other performance indicators (ratio of 1st to 2nd or 3rd choice antimicrobials and corticosteroids) did not change significantly. These results show how an evidence-based intervention program to foster adherence to an existing veterinary clinical practice guideline achieved a significant reduction in antimicrobial prescriptions by swine veterinarians.

Indexed as

Anti-Bacterial AgentsAntimicrobial StewardshipGuideline AdherenceStreptococcal InfectionsStreptococcus suisSwine DiseasesVeterinariansWeaningAnimalsAnti-Infective AgentsHumansNetherlandsSwineAnti-Bacterial AgentsAnti-Infective AgentsAntimicrobial resistanceAntimicrobial stewardshipImplementation interventionLivestockPerformance indicatorsVeterinary guidelines

Identifiers

PMID39613833
PMCPMC11607450

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.