ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026
Evaluating the relationship between obstructive sleep apnea and all-cause and cause-specific mortality in adults with and without metabolic syndrome using real-world data.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Association between visceral fat area and heart rate variability in high altitude migrants with OSA: the mediating effect of insulin resistance.Lipids in health and disease · 2025Article
- A predictive model for metabolic syndrome in a community-based population with sleep apnea: a secondary prevention screening tool using simple and accessible indicators.Frontiers in nutrition · 2025Article
Corrections and comments
- Erratum issued
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimObstructive Sleep Apnea (OSA) is a prevalent sleep disorder linked to increased risks of cardiovascular and metabolic disorders, significantly raising overall mortality rates. This study explores the associations between OSA and mortality in adults with and without Metabolic Syndrome (MetS) using data from the National Health and Nutrition Examination Survey (NHANES). METHODS AND
resultsData from NHANES (2005-2008) were analyzed, including 11,759 participants. OSA and MetS were identified based on survey responses and standard clinical criteria. Cox proportional hazards regression models were used to assess the relationship between OSA and mortality, adjusting for covariates. OSA was associated with significantly higher all-cause and cardiovascular mortality in the general population. In individuals without MetS, OSA was linked to higher all-cause and cardiovascular mortality. However, in individuals with MetS, OSA did not significantly affect mortality rates after adjusting for covariates.
conclusionOSA increases the risk of all-cause and cardiovascular mortality in individuals without MetS, emphasizing the need for early identification and management, particularly in those without metabolic comorbidities. In contrast, the impact of OSA on mortality in individuals with MetS may be mitigated by medical monitoring and treatment. These findings highlight the importance of individualized clinical strategies and call for further research to explore the underlying mechanisms of OSA-MetS interactions.
Indexed as
Identifiers
39613855What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.