Evidence mapPaperPMID 39617638Full record

ArticlePhysiological reports2024

Exercise during pregnancy modulates infant cellular and whole-body adiposity.

Alex Claiborne, Filip Jevtovic, Donghai Zheng, Cody Strom, Breanna Wisseman, Samantha McDonald, Edward Newton, Steven Mouro, James DeVente, Joseph A Houmard and 2 more

Abstract read
In one paragraph

Article in Physiological reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Maternal exercise alters placental proteome in an exercise mode-specific manner.American journal of physiology. Endocrinology and metabolism · 2025
    Trial
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Alex ClaiborneDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Filip JevtovicDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.ORCID 0000-0002-5486-2736
Donghai ZhengDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Cody StromDepartment of Kinesiology and Sport, University of Southern Indiana, Evansville, Indiana, USA.
Breanna WissemanDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Samantha McDonaldSchool of Kinesiology and Recreation, Illinois State University, Normal, Illinois, USA.
Edward NewtonDepartment of Obstetrics & Gynecology, East Carolina University, Greenville, North Carolina, USA.
Steven MouroDepartment of Obstetrics & Gynecology, East Carolina University, Greenville, North Carolina, USA.
James DeVenteDepartment of Obstetrics & Gynecology, East Carolina University, Greenville, North Carolina, USA.
Joseph A HoumardDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Nicholas T BroskeyDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.
Linda E MayDepartment of Kinesiology, East Carolina University (ECU), Greenville, North Carolina, USA.ORCID 0000-0002-8231-2280

Funding

American Heart Association (AHA) 15GRNT24470029East Carolina University (ECU)Thrasher Research Fund (TRF) 02154
6 · The paper itself

Abstract

Non-pharmaceutical interventions are needed to target the growing intergenerational cycle of obesity. We aimed to determine whether in utero exposure to different exercise doses during pregnancy directly reduces infant cellular and whole-body adiposity. Pregnant women completed ~24 weeks of supervised exercise training; for standardization of exercise analysis (frequency, intensity, time, and volume-FIT-V), metrics were assessed from 16 to 36 weeks. Mesenchymal stem cells (MSC) collected from the umbilical cord at delivery underwent 21 days of adipogenic differentiation, then Oil Red O staining for lipid content. Infant body composition was measured at 1 month of age. ANCOVA and Pearson correlations determined the influence of prenatal exercise on infant adiposity. Exercise decreased infant MSC lipid content (p = 0.01) and body fat percentage (p = 0.009) irrespective of dose. Total exercise volume throughout pregnancy was negatively correlated with infant body fat % (R

Indexed as

AdiposityExerciseMesenchymal Stem CellsAdipogenesisAdultFemaleHumansInfantInfant, NewbornMalePregnancyadiposeFIT‐Vmesenchymal stem celloffspringprenatal exercise

Identifiers

PMID39617638
PMCPMC11608828

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.