Evidence map›Paper›PMID 39617693›Full record

SynthesisJournal of traditional Chinese medicine = Chung i tsa chih ying wen pan2024

Chinese patent medicine for atherosclerosis: a systematic review and Meta-analysis of randomized controlled trials.

X U Jian, Liu Yuntao, Luo Zhihao, Zhao Zhen, Wang Dawei, Liu Qing

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

X U JianGuangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, the Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Liu YuntaoGuangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, the Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Luo ZhihaoGuangdong Provincial Hospital of Chinese Medicine-Hainan Hospital, Haikou 570100, China.
Zhao ZhenGuangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine-Zhuhai Hospital, State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Wang DaweiGuangdong Provincial Hospital of Chinese Medicine, State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.
Liu QingGuangdong Provincial Hospital of Chinese Medicine, Guangdong Provincial Hospital of Chinese Medicine-Zhuhai Hospital, State Key Laboratory of Traditional Chinese Medicine Syndrome, The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou 510006, China.

Funding

National Natural Science Foundation of China: Regulation of nanomedicine on the immune microenvironment in the macrophage-rich area of arterial plaques based on IL-17 immunity 82274279, to Q.L.
6 · The paper itself

Abstract

objectiveTo synthesize the evidence from randomized controlled trials (RCTs) to assess the efficacy and safety of Chinese patent medicine (CPM) on atherosclerosis (AS) or with a high risk of atherosclerosis.

methodsAll RCTs in three databases (PubMed, EMBASE, and Cochrane Library) were included from the inception of the database to September 20, 2019. The methodological evaluation of the included trials was carried out using the Cochrane Collaboration Risk of Bias Tool. Meta-analysis was conducted using RevMan 5.3 software. The Grading of Recommendations Assessment, Development and Evaluation (GRADE) methodology was used to evaluate the quality of evidence.

resultsEighteen RCTs were included, involving a total of 3885 patients with AS or with a high risk of AS. Most trials had favorable methodology. Meta-analysis suggested significant differences in clinical endpoint (

conclusionCPM could have certain clinical efficacy in the treatment of AS. However, more double-blinded placebo-controlled RCTs are required in further evaluations to provide stronger evidence.

Indexed as

AtherosclerosisDrugs, Chinese HerbalRandomized Controlled Trials as TopicFemaleHumansMaleMiddle AgedDrugs, Chinese HerbalatherosclerosisChinese patent medicineflow-mediated dilationintima-media thicknessmeta-analysissafety

Identifiers

PMID39617693
PMCPMC11589558

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.