ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024
Association Between Metabolic and Obesity Phenotypes and Diabetes Risk in Children and Adolescents.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Body Adiposity Indices, Adipokines Profile, and CNR1 Polymorphisms in Atypical Phenotypes of Obesity.Metabolites · 2026Article
- The Natural History of Prediabetes and Cardiovascular Disease in the Pediatric Population.Biomedicines · 2026Review
- Impact of pediatric obesity on abdominal surgery outcome: a narrative review.Frontiers in pediatrics · 2026Review
- SERUM LncRNA SNHG16: A Biomarker for Diagnosing Childhood Obesity and Predicting Its Progression to Metabolic Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Beyond Cardiometabolic: Health Disorders Risk in Metabolically Healthy Obese Children - A Systematic Review and Meta-Analysis of 19,119 Children.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Diabetes is a significant public health concern worldwide, having increased rapidly in recent decades among younger generations. The correlation between metabolic/obesity phenotypes and the development of pre-diabetes in children and adolescents remains unclear. Methods: This study aimed to explore this association within a cohort of 1,524 subjects aged 7 to 18 years. Subjects were categorized into four groups based on their metabolic and obesity status: Metabolically Unhealthy with Normal Body Weight (MUNW), Metabolically Healthy Overweight/Obesity (MHO), Metabolic Healthy with Normal Body Weight (MHNW), and Metabolically Unhealthy Overweight/Obesity (MUO). Physical parameters such as body mass, as well as biochemical markers including blood pressure, fasting glucose, triglycerides, and high-density lipoprotein cholesterol, were measured. Results: A total of 61.9% of children were within the normal range for both body weight and metabolism (MHNW), while 24.4% were classified as MUNW, 5.7% as MHO, and 8% as MUO. The risks of diabetes in the MUNW and MUO groups were 8.89 and 9.18 times higher than in the MHNW group for boys, and 8.15 and 11.24 times higher for girls (P<0.05). Conclusion: These findings suggest that abnormal metabolism, irrespective of body weight, significantly increases the risk of diabetes, while obesity alone does not predict pre-diabetes unless accompanied by metabolic dysregulation. Metabolic markers may serve as more sensitive indicators for assessing diabetes risk in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.