ArticleNeuropsychiatric disease and treatment2024
Anxious Depression in Major Depressive Disorder: Key Influences and Prevalence in Chinese Hospitalized Patients.
Article in Neuropsychiatric disease and treatment, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Prevalence and related factors of anxiety symptoms in patients with major depressive disorder and a history of recent suicide attempts: cross-sectional study.BJPsych open · 2026Article
- Do immune system and microbiome-gut-brain axis interactions associate with major depressive disorder?Journal of translational medicine · 2025Review
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4 authors.
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Abstract
Background: Anxious depression (AUD) is a common subtype of major depressive disorder (MDD) and has a significant negative impact on disease progression and patient prognosis. Our study aimed to determine the frequency of AUD in Chinese patients with MDD during their first hospitalization and to identify factors that may influence the emergence and intensity of these AUD. Methods: This study enrolled 981 Chinese MDD patients on their inaugural hospital admission. Data on demographic details, clinical profiles, and psychological symptoms-such as depression, anxiety, psychosis, and illness severity scores-were gathered and examined. Results: The study found that 10.30% of the target population exhibited AUD. Compared with the non-AUD group, the AUD group had higher scores on Hamilton Depression Scale (HAMD), Positive symptom subscale of the Positive and Negative Symptom Scale (PSS), and Clinical Global Impression Scale - Severity of Illness (CGI-SI) and higher levels of fasting blood glucose (FBG), total cholesterol (TC), body mass index (BMI), systolic blood pressure (SBP) and diastolic blood pressure (DBP). In addition, higher scores of HAMD, PSS and CGI-SI were risk factors for increasing the severity of anxiety, higher TC level was contrary. Conclusion: This study reveals the prevalence of AUD in hospitalized patients with MDD and identifies clinical factors that contribute to the onset and progression of AUD. Reporting these clinical features may help establish potential markers for early recognition and intervention.
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