Evidence map›Paper›PMID 39619643›Full record

ReviewCurrent research in food science2024

Human toxicity of polybrominated diphenyl ethers (PBDEs) and their derivatives: A comprehensive review.

Jiuhe Gao, Zesen Xie, Ziyan Wang, Yingxin Yu, Zenghua Qi, Xi Yu, Tian Zhong, Ling Wang, Ke Feng, Ye Peng and 1 more

Abstract readReview
In one paragraph

Review in Current research in food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiuhe GaoFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Zesen XieFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Ziyan WangFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Yingxin YuGuangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, 510006, China.
Zenghua QiGuangdong-Hong Kong-Macao Joint Laboratory for Contaminants Exposure and Health, Guangdong Key Laboratory of Environmental Catalysis and Health Risk Control, Institute of Environmental Health and Pollution Control, Guangdong University of Technology, Guangzhou, 510006, China.
Xi YuFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Tian ZhongFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Ling WangFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Ke FengFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Ye PengFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.
Ying XiaoFaculty of Medicine, Macau University of Science and Technology, Taipa, Macao SAR, 999078, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Polybrominated biphenyl ethers (PBDEs) have been pervasively used as an additive flame retardant in various fields. The nature of environmental persistence, bioaccumulation, and potential toxicity attracted attention worldwide and became a threat to both the ecosystem and human health. Originally, PBDEs are produced in chemical factories. PBDEs exposure was mainly by ingestion of contaminated food products, followed by inhalation of particles containing deposited PBDEs. This review concluded the liver injuries, thyroid hormone disorder, neurotoxicity, genotoxicity and immune system disorders as five major toxicities via overexposure to PBDEs and their toxic mechanism. PBDEs can cause severe consequences by inducing mitochondria dysfunction and oxidative stress, disrupting neurotransmitter metabolism and compromising the integrity of DNA, etc. This review presented an in-depth analysis of the most recent toxicological evidence to offer suggestions for future studies to control human overexposure to PBDEs.

Indexed as

Exposure pathwaysFood chainPBDEs derivativesPolybrominated biphenyl ethersToxicities

Identifiers

PMID39619643
PMCPMC11605445

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.