Evidence map›Paper›PMID 39619690›Full record

ArticleFrontiers in microbiology2024

A nested case-control study on the association of gut virome in early pregnancy and gestational diabetes mellitus.

Xinrui Wu, Xinpeng Liu, Wenbo Xu, Wenhui Chen, Zixin Zhong, Hongzhuan Tan, Tianyu Xiang

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinrui WuSchool of Medicine, Jishou University, Jishou, China.
Xinpeng LiuSchool of Medicine, Jishou University, Jishou, China.
Wenbo XuSchool of Medicine, Jishou University, Jishou, China.
Wenhui ChenSchool of Medicine, Jishou University, Jishou, China.
Zixin ZhongXiangya School of Public Health, Central South University, Changsha, China.
Hongzhuan Tan *Xiangya School of Public Health, Central South University, Changsha, China.
Tianyu Xiang *Xiangya School of Public Health, Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Recent studies have increasingly shown the connection between gut microbiome and gestational diabetes mellitus (GDM). However, no studies have explored the relationship between the gut virome and GDM, and the underlying mechanism remains unknown. Methods: We performed a nested case-control study within a follow-up cohort, enrolling 51 patients with GDM and 51 healthy controls. Shotgun metagenomics sequencing was used to explore gut virome profiles during early pregnancy. Results: Diversity analysis revealed no difference in the overall gut virome composition between two groups, however, we found greater abundance of Conclusion: This study is the first to investigate the relationship between the gut virome and GDM as well as the cross-kingdom correlation between gut viruses and bacteria in GDM. Our findings could enhance strategies for preventing and treating GDM from the perspective of gut microbiome, offering valuable insights into its pathogenesis.

Indexed as

cross-kingdom correlationgestational diabetes mellitusgut microbiomegut viromenested case-control studyprediction model

Identifiers

PMID39619690
PMCPMC11604603

What Socratic holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.