Evidence mapPaperPMID 39620333Full record

ReviewCurrent diabetes reviews2025

Diabetes Mellitus: Exploring Biomarkers, Complications, and Therapeutic Strategies with a Spotlight on Cyanobacterial Bioactive Compounds - A Comprehensive Review.

Suhail Ahmad, Salman Akhtar, Mohammad Amjad Kamal, Alvina Farooqui

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current diabetes reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Suhail AhmadDepartment of Bioengineering, Integral University, Lucknow, Uttar Pradesh, 226026, India.ORCID 0000-0003-3358-1094
Salman AkhtarDepartment of Bioengineering, Integral University, Lucknow, Uttar Pradesh, 226026, India.ORCID 0000-0003-2921-3950
Mohammad Amjad KamalNovel Global Community Educational Foundation, Hebersham, NSW 2770, Australia.ORCID 0000-0003-0088-0565
Alvina FarooquiDepartment of Bioengineering, Integral University, Lucknow, Uttar Pradesh, 226026, India.ORCID 0000-0002-7260-0414

Funding

Integral University, Lucknow- 226026, INDIA IU/R&D/2023-MCN IU/R&D/2023-MCN0001907
6 · The paper itself

Abstract

Diabetes, regarded as a prevalent metabolic disorder with multifactorial origins, contributes to a myriad of global complications. These cumulate an elevated susceptibility to kidney failure, nerve impairment, blindness, atherosclerosis, heart ailments, and even strokes. Recent investigations underscore the diverse roles of associated biomarkers in diabetes progression. Among these are biomarkers for diabetes mellitus such as DPP-4, PPAR-ϒ, SGLT-2, α-amylase, and α-glucosidase, which are linked to the onset of diabetes and its related problems. As a result of undesirable adverse consequences linked to extant synthetic antidiabetic medications, research attention is increasingly directed towards formulating natural antidiabetic drugs, aiming for enhanced efficacy and reduced complications. Cyanobacteria stand out as a pivotal repository of natural bioactive metabolites extensively harnessed for pharmaceutical and nutraceutical development. The potent bioactive compounds sourced from cyanobacteria hold substantial promise, kindling high expectations in scientific research and presenting vast prospects for drug discovery and advancement. Some of these bioactive compounds have demonstrated impressive effectiveness, displaying successful applications across various phases of clinical trials. This review strives to provide a more precise understanding of diabetes mellitus, encompassing its clinical manifestation, epidemiological data, complications, and prevailing treatment modalities. The objective of this review is to contribute researchers and readers an enhanced and accurate understanding of diabetes mellitus by covering its clinical manifestation, epidemiological evidence, difficulties, and prevailing therapeutics possibilities.

Indexed as

Biological ProductsCyanobacteriaDiabetes ComplicationsDiabetes MellitusHypoglycemic AgentsAnimalsBiomarkersHumansBiological ProductsBiomarkersHypoglycemic Agentsantioxidantsbioactive compounds.biomarkerscyanobacterial strainsDiabetes mellitusDPP-4PPAR-ySGLT-2type 2 diabetes mellitusα-amylaseα-glucosidase

Identifiers

PMID39620333

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.