Evidence map›Paper›PMID 39621250›Full record

ArticleJournal of microbiology (Seoul, Korea)2024

Gut Microbiota Dysbiosis Facilitates Susceptibility to Bloodstream Infection.

Xiaomin Lin, Chun Lin, Xin Li, Fen Yao, Xiaoling Guo, Meimei Wang, Mi Zeng, Yumeng Yuan, Qingdong Xie, Xudong Huang and 1 more

Abstract read
In one paragraph

Article in Journal of microbiology (Seoul, Korea), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. A review of bloodstream infections-pathogens, pathogenesis, diagnostic strategies, treatment methods-challenges and future aspects.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026
    Review
  4. Antibiotic therapy in febrile neutropenia in haematological patients: current considerations and future challenges.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2026
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiaomin LinDepartment of Clinical Laboratory, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China.
Chun LinDepartment of Clinical Laboratory, The First Affiliated Hospital of Shantou University Medical College, Shantou, 515041, People's Republic of China.
Xin LiDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Fen YaoDepartment of Pharmacology, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Xiaoling GuoDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Meimei WangDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Mi ZengDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Yumeng YuanDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Qingdong XieDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China.
Xudong HuangDepartment of Clinical Laboratory, Jieyang People's Hospital, Jieyang, 522000, Guangdong, People's Republic of China.
Xiaoyang JiaoDepartment of Cell Biology and Genetics, Shantou University Medical College, Shantou, 515041, Guangdong, People's Republic of China. xyjiao@stu.edu.cn.

Funding

Shantou Science and Technology Project 201224106490150
6 · The paper itself

Abstract

To study the role of intestinal flora in the development of bloodstream infections (BSIs). 42 patients and 19 healthy controls (HCs) were screened into the study and their intestinal flora was measured by 16S rRNA gene sequencing. The bacterial diversity was significantly lower in the BSI group compared with that in the HCs (P < 0.001), and beta diversity was significantly differentiated between the two groups (PERMANOVA, P = 0.001). The four keystone species [Roseburia, Faecalibacterium, Prevotella, and Enterococcus (LDA > 4)] differed significantly between the two groups. Dysbiosis of fecal microbial ecology is a common condition present in patients with BSI. The proliferation of certain pathogens or reduction of SCFA-producing bacteria would cause susceptibility to BSI.

Indexed as

BacteriaDysbiosisFecesGastrointestinal MicrobiomeRNA, Ribosomal, 16SAdultAgedBacteremiaDisease SusceptibilityDNA, BacterialFemaleHumansMaleMiddle AgedDNA, BacterialRNA, Ribosomal, 16S16S rRNA gene sequencingBloodstream infectionIntestinal floraPathogen

Identifiers

PMID39621250
PMCPMC11652583

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.