SynthesisPloS one2024
Effects of aerobic, resistance and combined training on endothelial function and arterial stiffness in older adults: A systematic review and meta-analysis.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Effects of different exercise modalities and doses on arterial stiffness in individuals with overweight and obesity: a systematic review and Bayesian dose-response meta-analysis.BMC sports science, medicine & rehabilitation · 2026Pooled it
- Effects of concurrent training on body composition, metabolic, and inflammatory in postmenopausal women: a meta-analysis.BMC women's health · 2026Pooled it
- Can resistance training alone or resistance training combined with aerobic training improve arterial stiffness, endothelial function, and other vascular function indicators in adults with hypertension or overweight/obesity-related vascular risk? A systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2026Pooled it
- Arterial stiffness adaptations to chronic resistance and aerobic exercise: a systematic review of exercise modalities.Frontiers in public health · 2025Pooled it
- Pooled it
- Effects of aquatic exercise on arterial stiffness and endothelial function in adults: A systematic review and meta-analyses.PloS one · 2025Pooled it
- Effects of exercise on pulse wave velocity in hypertensive and prehypertensive patients: a systematic review and meta-analysis of randomized controlled trials.Frontiers in cardiovascular medicine · 2025Pooled it
- Resistance training and subcortical vascular cognitive impairment: A 12-month randomized trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026Trial
- Low-frequency resistance training enhances 2D strain-derived carotid strain and strain rate: a novel longitudinal application of strain imaging in healthy middle-aged females.European journal of applied physiology · 2026Article
- Effects of Resistance Training on Systolic and Diastolic Blood Pressure in Hypertensive Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of clinical medicine · 2026Review
- Postpartum cardio-obstetrics rehabilitation program for women after hypertensive pregnancy: A single-arm proof-of-concept study.Hypertension research : official journal of the Japanese Society of Hypertension · 2026Article
- Cerebral blood flow regulation, central arterial stiffness and traumatic brain injury: Effects of aerobic exercise training.Experimental physiology · 2026Review
- Inflammatory mediation of aerobic, resistance, and combined exercise effects on the vascular elasticity of obese women.iScience · 2026Article
- Exercise in CKM syndrome progression: a stage-specific approach to cardiovascular, metabolic, and renal health.Cardiovascular diabetology · 2025Review
- Effect of a 12-week bungy pump training on cardiorespiratory fitness, metabolic syndrome factors and body composition in postmenopausal women.Scientific reports · 2025Article
- Even a cold stone will warm up if you sit on it for 3 years.Hypertension research : official journal of the Japanese Society of Hypertension · 2025Article
- Arteries and Hearts in Motion: Sex Differences in Exercise-Mediated Protection Against Atherosclerotic Cardiovascular Disease Risk.Current atherosclerosis reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We conducted a systematic review of randomized clinical trials evaluating the effects of aerobic, resistance and/or combined training on flow-mediated dilation (FMD) and/or pulse wave velocity (PWV) in older adults. The studies were selected from the electronic databases PubMed, Cochrane, LILACS, EMBASE, Web of Science, and the gray literature. We assessed the studies using Cochrane risk of bias (RoB2) tool and the GRADE tool. The GRADE assessment showed moderate quality of evidence for aerobic training and resistance training and very low for combined training. The measures of effects are presented as mean differences of the intervention group versus the control group and related 95% confidence intervals (95% CIs) pooled by a random-effects model using an inverse variance method. Our analysis of 24 RCTs (Intervention group [n = 251]: 67.7 ± 5.6 years old; control group [n = 228]: 68.7 ± 5.9 years old) showed that aerobic training was effective to improve FMD (0.64% [95% CI 0.24 to 1.03], p = 0.002) and PWV (-1.21 m/s [95% CI -1.37 to -1.05], p< 0.001) by compared to the control group. The subgroup analyses showed no FMD differences following aerobic training in healthy adults when compared to those with any health condition. Combined training was effective in improving FMD (0.60% [95% CI 0.50 to 0.71], p< 0.001) and PWV (-0.79 m/s [95% CI -1.23 to -0.35], p = 0.002). But these same parameters did not show any improvement in response to resistance training. A major limitation of this study is that the analysis to evaluate the effect of resistance training on PWV include only one study, and no inferences could be made from the data. Aerobic and combined training, but not resistant training, improve flow-mediated dilation and pulse wave velocity in the elderly. PROSPERO: CRD42021275282.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.