Evidence mapPaperPMID 39624049Full record

ReviewMaterials today. Bio2024

Construction of vascular grafts based on tissue-engineered scaffolds.

Zhongliang Lang, Tianao Chen, Shilu Zhu, Xizhi Wu, Yongqi Wu, Xiaoping Miao, Qiang Wang, Liping Zhao, Zhiqiang Zhu, Ronald X Xu

Abstract readReview
In one paragraph

Review in Materials today. Bio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhongliang LangDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, PR China.
Tianao ChenSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Shilu ZhuSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Xizhi WuSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Yongqi WuSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Xiaoping MiaoSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.
Qiang WangDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, PR China.
Liping ZhaoDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, PR China.
Zhiqiang ZhuDepartment of Plastic Surgery, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230001, PR China.
Ronald X XuSchool of Biomedical Engineering, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, 230026, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) ranks among the leading causes of morbidity and mortality globally, primarily due to arterial occlusive disease. Vascular bypass remains the cornerstone of treatment; however, many patients lack suitable autologous vessels (e.g., saphenous vein) for grafting. Tissue-engineered vascular grafts (TEVGs) provide a viable alternative capable of integrating, remodeling, and repairing host vessels, responding to mechanical and biochemical stimuli. Currently, preparation methods for TEVGs are mainly categorized into scaffold-free and scaffold-based approaches. Scaffold-free methods exhibit comparatively weaker mechanical properties and limited research progress, whereas scaffold-based approaches show more promising applications due to their superior mechanical properties and biocompatibility. This review examines current research progress in materials, fabrication processes, functionalized modifications, cell implantation, and animal and clinical experiments for scaffold-based preparation of TEVGs. By exploring current challenges and future perspectives in this field, we expect to provide new insights into TEVGs development and expedite their clinical applications.

Indexed as

Blood vesselFabricationScaffoldTissue engineeringVascular grafts

Identifiers

PMID39624049
PMCPMC11609327

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.