ArticleHeliyon2024
CFD analysis of non-Newtonian blood flow through human carotid artery bifurcation: Carotid sinus susceptible to atherosclerosis.
Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Ophthalmic Artery Morphology and Hemodynamics in Ocular Ischemic Syndrome: A Computational Fluid Dynamics and Particle Image Velocimetry Study.Investigative ophthalmology & visual science · 2026Article
- Comparative Analysis of Open-Source Finite Element Method Solvers for Computational Fluid Dynamics Performance in a Carotid Artery Model.Journal of biomechanical engineering · 2026Article
- Relationship Between Carotid Artery Remodeling Characteristics and Early Carotid Atherosclerosis: An Ultrasonographic Multicenter Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Fat accumulation on the arteries' walls has become a serious health concern. This study conducted an in-depth hemodynamic analysis to identify the regions of a human carotid artery most susceptible to fat accumulation or atherosclerosis, considering the following factors: blood velocity, secondary flow regions, pressure, and wall shear stress. The hemodynamic analysis used a generalized geometric model to analyze these factors at various locations within the carotid bifurcation over different time points. Results showed that the bifurcation region is comparatively more affected by the factors contributing to atherosclerosis. Especially, the sinus region experiences all the key factors: a larger secondary flow, higher blood pressure, lower mean WSS, and lower fluctuation in temporal WSS. The findings indicate that the bifurcation region, particularly the sinus is prone to fat accumulation. These results are consistent with clinical observations, emphasizing the bifurcation and sinus regions as key sites for plaque accumulation. Insights from this analysis will serve as a foundation for optimizing geometric models of bifurcated arteries to improve blood flow and, consequently, reduce the risk of atherosclerosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.