Evidence map›Paper›PMID 39624479›Full record

ReviewAmerican journal of preventive cardiology2024

Lipoprotein(a) throughout life in women.

Pablo Corral, María Gabriela Matta, Carlos Aguilar-Salinas, Roopa Mehta, Gabriela Berg, Massimiliano Ruscica, Laura Schreier

Abstract readReview
In one paragraph

Review in American journal of preventive cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Lipoprotein(a) and coronary artery disease: The need for universal screening - A case-based review.American heart journal plus : cardiology research and practice · 2025
    Review
  14. Review
  15. Article
  16. Article
  17. Review
  18. Position Statement on Cardiometabolic Health Across the Woman's Life Course - 2025.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pablo CorralFASTA University, Pharmacology and Research Department. Instituto Investigaciones Clínicas (IIC), Mar del Plata, Argentina.
María Gabriela MattaFASTA University, Pharmacology and Research Department. Instituto Investigaciones Clínicas (IIC), Mar del Plata, Argentina.
Carlos Aguilar-SalinasUnidad de Investigación de Enfermedades Metabólicas. Departamento de Diabetes y Metabolismo. Dirección de Investigación. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Tecnológico de Monterrey, Escuela de Medicina y Ciencias de la Salud, México City, Mexico.
Roopa MehtaUnidad de Investigación de Enfermedades Metabólicas. Departamento de Diabetes y Metabolismo, México City, Mexico.
Gabriela BergUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Instituto de Fisiopatología y Bioquímica Clínica (INFIBIOC-UBA), Laboratorio de Lípidos y Aterosclerosis, Buenos Aires, Argentina.
Massimiliano RuscicaDepartment of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", Università degli Studi di Milano, Milan, Italy.
Laura SchreierUniversidad de Buenos Aires, Facultad de Farmacia y Bioquímica, Instituto de Fisiopatología y Bioquímica Clínica (INFIBIOC-UBA), Laboratorio de Lípidos y Aterosclerosis, Buenos Aires, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipoprotein (a) [Lp(a)] is a lipoprotein with multiple deleterious characteristics and is a recognized cardiovascular (CV) risk factor. The pro-atherogenic, pro-thrombotic, and pro-inflammatory features of Lp(a) are associated not only with atherosclerotic vascular disease but also with aortic valve calcification and all-cause mortality. One of the most interesting aspects of Lp(a) is that its level is determined by genetics in more than 90% of cases, with lifestyle habits having very little influence. Therefore, the recommendation is to test it, at least, once in a lifetime. Contrary to previous beliefs, evidence in recent decades has shown that women have the same or even greater CV risk than men of the same age, attributed to female sex hormones. Different stages of a woman's life can impact on Lp(a) levels, from newborn to menopause, including other critical moments such as menarche and pregnancy. The main objective of this review is to describe and analyze the effect of different specific periods of a woman's life on Lp(a) levels and the potential clinical relevance on their CV risk.

Indexed as

Lipoprotein(a)Lipoprotein(a) variabilityWomen

Identifiers

PMID39624479
PMCPMC11609252

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.