Evidence map›Paper›PMID 39625784›Full record

ArticleJournal of the American Society of Nephrology : JASN2025

Genotype-First Analysis in an Unselected Health System-Based Population and Phenotypic Severity of COL4A5 Variants.

McKenzie Zellers, Kaushal Solanki, Melissa A Kelly, Karyn M Murphy, Kyle Retterer, H Lester Kirchner, Ion Dan Bucaloiu, Bryn Moore, Tooraj Mirshahi, Alexander R Chang

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Kidney international reports · 2025
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

McKenzie ZellersGeisinger Commonwealth School of Medicine, Scranton, Pennsylvania.
Kaushal SolankiDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0001-9119-969
Melissa A KellyDepartment of Genomic Health, Geisinger, Danville, Pennsylvania.ORCID 0000-0003-4708-2261
Karyn M MurphyGeisinger, Danville, Pennsylvania.ORCID 0000-0002-8676-3337
Kyle RettererGeisinger, Danville, Pennsylvania.ORCID 0000-0001-5252-2001
H Lester KirchnerDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0002-2557-6749
Ion Dan BucaloiuDepartment of Nephrology, Geisinger, Danville, Pennsylvania.ORCID 0000-0003-2172-4035
Bryn MooreDepartment of Genomic Health, Geisinger, Danville, Pennsylvania.ORCID 0000-0002-8758-7611
Tooraj MirshahiDepartment of Genomic Health, Geisinger, Danville, Pennsylvania.ORCID 0000-0002-0754-3820
Alexander R ChangDepartment of Population Health Sciences, Geisinger, Danville, Pennsylvania.ORCID 0000-0002-8114-7447

Funding

An integrated approach to study GPCR variants associated with complex diseasesR01GM111913 · NIGMS · GEISINGER CLINIC · PI MIRSHAHI, TOORAJ, ROBISHAW, JANET D · 2015 to 2018
$2.1M
NIGMS NIH HHS GM111913NIGMS NIH HHS R01 GM111913
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alport syndromeCKDclinical epidemiologyESKDgenetic kidney diseasekidney failure

Identifiers

PMID39625784
PMCPMC12147960

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.