Evidence map›Paper›PMID 39626878›Full record

ReviewJournal of Zhejiang University. Science. B2024

Prefrontal cortical circuits in social behaviors: an overview.

Wei Cao, Huiyi Li, Jianhong Luo

Abstract readReview
In one paragraph

Review in Journal of Zhejiang University. Science. B, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei CaoInstitute of Brain Science and Department of Physiology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Huiyi LiInstitute of Brain Science and Department of Physiology, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou 311121, China.
Jianhong LuoAffiliated Mental Health Center & Hangzhou Seventh People's Hospital, School of Brain Science and Brain Medicine, Zhejiang University School of Medicine, Hangzhou 310013, China. luojianhong@zju.edu.cn.

Funding

the Autism Research Special Fund of Zhejiang Foundation for Disabled Persons 2022001 and 2023002the National Natural Science Foundation of China 81801355, U22A20306 and 3192010300the Non-profit Central Research Institute Fund of Chinese Academy of Medical Sciences 2023-PT310-01the Research and Development Program of Guangdong Province 2019B030335001
6 · The paper itself

Abstract

Social behaviors are fundamental and intricate functions in both humans and animals, governed by the interplay of social cognition and emotions. A noteworthy feature of several neuropsychiatric disorders, including autism spectrum disorder (ASD) and schizophrenia (SCZ), is a pronounced deficit in social functioning. Despite a burgeoning body of research on social behaviors, the precise neural circuit mechanisms underpinning these phenomena remain to be elucidated. In this paper, we review the pivotal role of the prefrontal cortex (PFC) in modulating social behaviors, as well as its functional alteration in social disorders in ASD or SCZ. We posit that PFC dysfunction may represent a critical hub in the pathogenesis of psychiatric disorders characterized by shared social deficits. Furthermore, we delve into the intricate connectivity of the medial PFC (mPFC) with other cortical areas and subcortical brain regions in rodents, which exerts a profound influence on social behaviors. Notably, a substantial body of evidence underscores the role of

Indexed as

Autism Spectrum DisorderPrefrontal CortexSchizophreniaSocial BehaviorAnimalsHumansInterneuronsReceptors, N-Methyl-D-AspartateReceptors, N-Methyl-D-AspartateAutism spectrum disorder (ASD)N-Methyl-D-aspartate receptor (NMDAR)Parvalbumin-positive interneuronPrefrontal cortex (PFC)Schizophrenia (SCZ)Social behavior

Identifiers

PMID39626878
PMCPMC11634449

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.