Evidence map›Paper›PMID 39628441›Full record

ArticleBioconjugate chemistry2024

Renally Excretable Molybdenum Disulfide Nanoparticles as Contrast Agents for Dual-Energy Mammography and Computed Tomography.

Lenitza M Nieves, Emily K Berkow, Katherine J Mossburg, Nathaniel H O, Kristen C Lau, Derick N Rosario, Priyash Singh, Xingjian Zhong, Andrew D A Maidment, David P Cormode

Abstract read
In one paragraph

Article in Bioconjugate chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Engineered MoSNanomaterials (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lenitza M NievesDepartment of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Emily K BerkowDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0009-0009-1425-1533
Katherine J MossburgDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0003-1317-4061
Nathaniel H ODepartment of Pharmaceutical Sciences, St. Joseph's University, Philadelphia, Pennsylvania 19131-1308, United States.
Kristen C LauDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Derick N RosarioDepartment of Biochemistry and Molecular Biophysics, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Priyash SinghDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Xingjian ZhongDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
Andrew D A MaidmentDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.
David P CormodeDepartment of Bioengineering, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States.ORCID 0000-0002-8391-9500

Funding

SUMMER UNDERGRADUATE PROGRAM TO EDUCATE RADIATION SCIENTISTS (SUPERS)R25CA140116 · NCI · UNIVERSITY OF PENNSYLVANIA · PI JAY FITZGERALD DORSEY · 2010 to 2026
$4.1M
Nanoparticle contrast agents for earlier breast cancer detectionR01CA227142 · NCI · UNIVERSITY OF PENNSYLVANIA · PI CORMODE, DAVID PETER · 2018 to 2022
$2.5M
Chemoprotectants for Head-Neck TherapeuticsR44CA140166 · NCI · REACTION BIOLOGY CORPORATION · PI MA, HAICHING · 2011 to 2012
$1.4M
Chemoprotectants for Head-Neck TherapeuticsR43CA140166 · NCI · REACTION BIOLOGY CORPORATION · PI MA, HAICHING · 2009 to 2009
$253k
CT imaging and therapy of inflammatory bowel disease via catalytic ceria nanoparticlesF31EB034165 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI ROSARIO, DERICK · 2022 to 2023
$94k
NCI NIH HHS R01 CA227142NCI NIH HHS R25 CA140116NCI NIH HHS R43 CA140166NCI NIH HHS R44 CA140166NIBIB NIH HHS F31 EB034165
6 · The paper itself

Abstract

Compared with conventional mammography, contrast-enhanced dual-energy mammography (DEM) can improve tumor detection for people with dense breasts. However, currently available iodine-based contrast agents have several drawbacks such as their contraindication for use with renal insufficiency, high-dose requirement, and suboptimal contrast production. Molybdenum disulfide nanoparticles (MoS

Indexed as

Contrast MediaDisulfidesMammographyMolybdenumNanoparticlesTomography, X-Ray ComputedAnimalsFemaleHumansKidneyMiceContrast MediaDisulfidesMolybdenummolybdenum disulfide

Identifiers

PMID39628441
PMCPMC11655252

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.