Evidence map›Paper›PMID 39629237›Full record

ArticleFrontiers in medicine2024

Beneficial effects of non-invasive physical plasma on human periodontal ligament cells

Benedikt Eggers, Lennard Seher, Jana Marciniak, Tristan Pauck, James Deschner, Sigrun Eick, Matthias Bernhard Stope, Franz-Josef Kramer, Erika Calvano Küchler, Christian Kirschneck and 2 more

Abstract read
In one paragraph

Article in Frontiers in medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Benedikt EggersDepartment of Oral, Maxillofacial and Plastic Surgery, University Hospital Bonn, Bonn, Germany.
Lennard SeherDepartment of Oral, Maxillofacial and Plastic Surgery, University Hospital Bonn, Bonn, Germany.
Jana MarciniakDepartment of Orthodontics, University Hospital Bonn, Bonn, Germany.
Tristan PauckDepartment of Gynecology and Gynecological Oncology, University Hospital Bonn, Bonn, Germany.
James DeschnerDepartment of Periodontology and Operative Dentistry, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Sigrun EickDepartment of Periodontology, School of Dental Medicine, University of Bern, Bern, Switzerland.
Matthias Bernhard StopeDepartment of Gynecology and Gynecological Oncology, University Hospital Bonn, Bonn, Germany.
Franz-Josef KramerDepartment of Oral, Maxillofacial and Plastic Surgery, University Hospital Bonn, Bonn, Germany.
Erika Calvano KüchlerDepartment of Orthodontics, University Hospital Bonn, Bonn, Germany.
Christian KirschneckDepartment of Orthodontics, University Hospital Bonn, Bonn, Germany.
Marjan Nokhbehsaim *Section of Experimental Dento-Maxillo-Facial Medicine, University Hospital Bonn, Bonn, Germany.
Svenja Beisel-Memmert *Department of Orthodontics, University Hospital Bonn, Bonn, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Periodontitis is a chronic inflammatory disease of the periodontium that can lead to the loss of affected teeth if left untreated. It is induced by a multifactorial process centered on microbial pathogens such as Fusobacterium nucleatum Methods: Initially, the solitary effect of NIPP was evaluated by measuring temperature and pH and analyzing reactive oxygen species (ROS). Additionally, DAPI and phalloidin staining were employed to investigate possible cytotoxic effects. The cells were pre-incubated with Results: NIPP alone had no significant effect on PDL cells. However, the Discussion: Thus, the utilization of NIPP may be regarded as a promising therapeutic strategy for the treatment of periodontal diseases.

Indexed as

antimicrobialcold plasmahuman periodontal ligament cellsnon-invasive physical plasmanon-thermal plasmaperiodontology

Identifiers

PMID39629237
PMCPMC11611554

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.