Evidence map›Paper›PMID 39629989›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Microwave Ablation Combined with Flt3L Provokes Tumor-Specific Memory CD8

Meixiang Wang, Jing Sang, Fengkuo Xu, Shulong Wang, Peng Liu, Ji Ma, Zhengtao Chen, Qi Xie, Zhigang Wei, Xin Ye

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Microwave ablation combined with dendritic cells enhances CD8Cancer immunology, immunotherapy : CII · 2026
    Article
  3. Article
  4. [Progress in the Immune Mechanism of Microwave Ablation Therapy for Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Microwave Ablation Combined with Flt3L Provokes Tumor-Specific Memory CD8Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  9. Review
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meixiang WangDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Jing SangDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Fengkuo XuDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Shulong WangShandong Academy of Preventive Medicine, Shandong Center for Disease Control and Prevention, 16992 Jingshi Road, Jinan, 250014, P. R. China.
Peng LiuDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Ji MaDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Zhengtao ChenSchool of Laboratory Animal & Shandong Laboratory Animal Center, Shandong First Medical University & Shandong Academy of Medical Sciences, 6699 Qingdao Road, Jinan, 250014, P. R. China.
Qi XieDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Zhigang WeiDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.
Xin YeDepartment of Oncology, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Provincial Lab for Clinical Immunology Translational Medicine in Universities, Shandong Lung Cancer Institute, 16766 Jingshi Road, Jinan, 250014, P. R. China.ORCID https://orcid.org/0000-0002-4906-7746

Funding

National Natural Science Foundation of China 82071740National Natural Science Foundation of China 82072028
6 · The paper itself

Abstract

For medically inoperable non-small cell lung cancer, microwave ablation (MWA) represents a super minimally invasive alternative treatment. However, tumor recurrence remains a concern. Here, it is demonstrated that the combination of MWA with Flt3L significantly inhibits tumor recurrence by CD8

Indexed as

Carcinoma, Non-Small-Cell LungCD8-Positive T-LymphocytesLung NeoplasmsMembrane ProteinsMicrowavesProgrammed Cell Death 1 ReceptorAnimalsCell Line, TumorDendritic CellsFemaleHumansImmune Checkpoint InhibitorsImmunologic MemoryMiceMice, Inbred C57BLTumor Microenvironmentflt3 ligand proteinImmune Checkpoint InhibitorsMembrane ProteinsProgrammed Cell Death 1 Receptordendritic cellsICOS‐ICOSL axismicrowave ablationnon‐small cell lung cancertumor‐specific memory CD8+ T cells

Identifiers

PMID39629989
PMCPMC11775548

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.