ArticleSleep & breathing = Schlaf & Atmung2024
Sex-specific impact of obstructive sleep apnea on peripheral blood mononuclear cells.
Article in Sleep & breathing = Schlaf & Atmung, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Sleep, Neural Circulatory Control, and Cardiovascular Disease: A Mechanistic Review.Arteriosclerosis, thrombosis, and vascular biology · 2026Review
- Sex Differences in Atherosclerotic Cardiovascular Disease Risk in Obstructive Sleep Apnea.Current atherosclerosis reports · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
purposeExperimental sleep disruption in healthy adults is more deleterious to immune function in females relative to males; however, it remains unknown if this translates to patients with obstructive sleep apnea (OSA). Thus, this study explored sex differences in peripheral blood mononuclear cells (PBMCs) from patients with untreated OSA.
methodsParticipants completed sleep studies to identify the presence of OSA via the apnea-hypopnea index (AHI). PBMCs were isolated, cryopreserved, and batch phenotyped via mass cytometry.
resultsFemales with (n = 6, AHI = 25.9 ± 21.4 events/hr, age = 37 ± 14yrs, BMI = 30.5 ± 7.4 kg/m
conclusionsOur data suggest that OSA increases the prevalence of cytotoxic NK cells and Tregs in females. The causes and downstream effects of these changes remain undetermined.
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Registered trials
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