Observational studyPloS one2024
Anesthetic technique and postoperative pulmonary complications (PPC) after Video Assisted Thoracic (VATS) lobectomy: A retrospective observational cohort study.
Observational study in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Predictors of Postoperative Pneumonia Following Anatomical Lung Resections in Thoracic Surgery.Journal of clinical medicine · 2025Article
- Effect of the tubeless approach on the non-operative lung in thoracic surgery: a retrospective cohort study.Journal of thoracic disease · 2025Article
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThoracic surgery is associated with an 8-10% incidence of postoperative pulmonary complications (PPCs). Introduction of minimally invasive Video-assisted thoracoscopic surgery (VATS) aimed to reduce pain related and pulmonary complications. However, PPCs remain a common cause of morbidity after VATS.
methodsThe American College of Surgeons National Surgical Quality Improvement Program database was searched for VATS lobectomy cases from 2017 to 2021 with General Anesthesia (GA) as the primary anesthetic technique. Cases were stratified into four groups-GA alone, GA+local, GA+Regional and GA+Epidural. Generalized linear regression models were used to examine whether PPCs differ by anesthetic technique, controlling for morbidity risk factors. The study's primary outcome was the occurrence of any PPC (pneumonia, reintubation or prolonged mechanical ventilation). The secondary outcome was length of hospital stay (LOS).
resultsA total of 15,084 VATS lobectomy cases were identified and 14,477 cases met inclusion criteria. The PPC rate was between 3.5-5.2%. There was no statistically significant difference in the odds of PPCs across the groups. Compared to the GA alone group, the regional and local group had significantly shorter LOS (9.1% and 5.5%, respectively, both ps < .001), whereas the epidural group had significantly longer LOS (18%, p < .001).
conclusionOur analysis suggests that the addition of regional or local anesthesia is associated with shorter LOS after VATS lobectomy. However, these techniques were not associated with lower PPC incidence. Future randomized controlled trials could help to elucidate the best anesthetic technique to reduce pain and enhance recovery.
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