Evidence map›Paper›PMID 39630866›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

An integrated picture of the structural pathways controlling the heart performance.

Ilaria Morotti, Marco Caremani, Matteo Marcello, Irene Pertici, Caterina Squarci, Pasquale Bianco, Theyencheri Narayanan, Gabriella Piazzesi, Massimo Reconditi, Vincenzo Lombardi and 1 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Spatial control of myosin regulatory light chain phosphorylation modulates cardiac thick filament mechanosensing.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. The Mechanism of Modulation of Cardiac Force by Temperature.International journal of molecular sciences · 2025
    Article
  7. An integrated picture of the structural pathways controlling the heart performance.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ilaria MorottiPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0009-0001-7119-5648
Marco CaremaniPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.
Matteo MarcelloPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0009-0002-5517-8618
Irene PerticiPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0003-4243-1573
Caterina SquarciPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0003-1864-8780
Pasquale BiancoPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0002-0705-4349
Theyencheri NarayananEuropean Synchrotron Radiation Facility, Grenoble 38043, France.ORCID 0000-0003-1957-1041
Gabriella PiazzesiPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0001-9324-2241
Massimo ReconditiPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0001-5065-924X
Vincenzo LombardiPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0003-2679-8308
Marco LinariPhysioLab, University of Florence, Sesto Fiorentino 50019, Italy.ORCID 0000-0001-6512-4897

Funding

European Joint Programme on Rare Diseases EJPRD19-126Fondazione Cassa di Risparmio di Firenze (Fondazione CR Firenze) 2020.1660Italian Ministry of University and Research P2022XPT32Next Generation EU Programme PE8-Age-Tt
6 · The paper itself

Abstract

The regulation of heart function is attributed to a dual filament mechanism: i) the Ca

Indexed as

ConnectinActin CytoskeletonActinsAnimalsCarrier ProteinsHeartMaleMyocardial ContractionMyocardiumMyosin Binding Protein CMyosinsPapillary MusclesRatsRats, Sprague-DawleyX-Ray DiffractionActinsCarrier ProteinsConnectinMyosin Binding Protein CMyosinsactincardiac muscle regulationmyosinmyosin-binding protein Ctitin

Identifiers

PMID39630866
PMCPMC11648670

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.