Evidence map›Paper›PMID 39633172›Full record

ArticleAnnals of surgical oncology2025

Outcomes for Patients with Obesity Undergoing Adrenalectomy for Pheochromocytoma: An International Multicenter Analysis.

Kevin Verhoeff, Alessandro Parente, Yanbo Wang, Nanya Wang, Zhicheng Wang, Maciej Śledziński, Andrzej Hellmann, Marco Raffaelli, Francesco Pennestrì, Mark Sywak and 70 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

80 authors.

Kevin Verhoeff *Department of Surgery, Division of General Surgery, University of Alberta, Faculty of Medicine and Dentistry, Edmonton, AB, Canada.
Alessandro Parente *Department of Surgery, Division of General Surgery, University of Alberta, Faculty of Medicine and Dentistry, Edmonton, AB, Canada. aleparen@gmail.com.ORCID http://orcid.org/0000-0001-5506-224X
Yanbo WangDepartment of Urology, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Nanya WangDepartment of Oncology, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Zhicheng WangDepartment of Urology, The First Affiliated Hospital of Jilin University, Changchun, Jilin, China.
Maciej ŚledzińskiDivision of General, Endocrine and Transplant Surgery, Medical University of Gdańsk, Gdańsk, Poland.
Andrzej HellmannDivision of General, Endocrine and Transplant Surgery, Medical University of Gdańsk, Gdańsk, Poland.
Marco RaffaelliUOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Centro di Ricerca in Chirurgia Endocrina e dell'Obesità, Università Cattolica del Sacro Cuore, Rome, Italy.
Francesco PennestrìUOC Chirurgia Endocrina e Metabolica, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Centro di Ricerca in Chirurgia Endocrina e dell'Obesità, Università Cattolica del Sacro Cuore, Rome, Italy.
Mark SywakEndocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, Sydney, NSW, Australia.
Alexander J PapachristosEndocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, Sydney, NSW, Australia.
Fausto F PalazzoDepartment of Endocrine Surgery, Hammersmith Hospital, London, UK.
Tae-Yon SungDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Byung-Chang KimDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Yu-Mi LeeDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Fiona EatockDepartment of Endocrine Surgery, Royal Victoria Hospital, Belfast, UK.
Hannah AndersonDepartment of Endocrine Surgery, Royal Victoria Hospital, Belfast, UK.
Maurizio IacoboneEndocrine Surgery Unit, Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.
Albertas DaukšaDepartment of Surgery, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Ozer MakayOzel Saglik Hospital, Centre of Endocrine Surgery, Izmir, Turkiye and School of Medicine, Aristoteleio University of Thessaloniki, Thessaloniki, Greece.
Yigit TurkDepartment of General Surgery, Division of Endocrine Surgery, Ege University Hospital, Izmir, Türkiye.
Hafize Basut AtalayDepartment of General Surgery, Division of Endocrine Surgery, Ege University Hospital, Izmir, Türkiye.
Els J M Nieveen van DijkumDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Anton F EngelsmanDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Isabelle HolscherDepartment of Surgery, Amsterdam UMC, University of Amsterdam, Cancer Center Amsterdam, Amsterdam, The Netherlands.
Gabriele MaterazziEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Leonardo RossiEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Chiara BecucciEndocrine Surgery Unit, University Hospital of Pisa, Pisa, Italy.
Susannah L ShoreDepartment of Endocrine and Breast Surgery, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, UK.
Clare FungDepartment of Endocrine and Breast Surgery, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, UK.
Alison WaghornDepartment of Endocrine and Breast Surgery, Royal Liverpool and Broadgreen University Hospitals Trust, Liverpool, UK.
Radu MihaiDepartment of Endocrine Surgery, Churchill Cancer Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Sabapathy P BalasubramanianDepartment of General Surgery, Sheffield Teaching Hospitals Foundation Trust, Sheffield, UK.
Arslan PannuDepartment of General Surgery, Sheffield Teaching Hospitals Foundation Trust, Sheffield, UK.
Shuichi TataranoDepartment of Urology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, Japan.
David Velázquez-FernándezServicio de Cirugía Endocrina y Laparoscopia Avanzada, Departamento de Cirugía, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Julie A MillerEndocrine Surgery Unit, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Hazel Serrao-BrownEndocrine Surgical Unit, Royal North Shore Hospital, Northern Sydney Local Health District, Sydney, NSW, Australia.
Yufei ChenDepartment of Surgery, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Marco Stefano DemarchiDepartment of Thoracic and Endocrine Surgery and Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Reza DjafarrianDepartment of Thoracic and Endocrine Surgery and Faculty of Medicine, University Hospitals of Geneva, Geneva, Switzerland.
Helen DoranDepartment of Endocrine Surgery, Salford Royal Hospital, Salford, UK.
Kelvin WangDepartment of Endocrine Surgery, Salford Royal Hospital, Salford, UK.
Michael J StechmanDepartment of Endocrine Surgery, University Hospital Wales, Cardiff, UK.
Helen PerryDepartment of Endocrine Surgery, University Hospital Wales, Cardiff, UK.
Johnathan HubbardDepartment of Endocrine Surgery, St Thomas' Hospital, London, UK.
Cristina LamasEndocrinology and Nutrition Department, Hospital Universitario de Albacete, Albacete, Spain.
Philippa MercerEndocrine Surgical Unit, Department of General Surgery, Christchurch Hospital, Christchurch, New Zealand.
Janet MacPhersonDepartment of Anaesthesia, Christchurch Hospital, Christchurch, New Zealand.
Supanut LumbiganonDepartment of Surgery, Division of Urology, Khon Kaen University, Khon Kaen, Thailand.
María CalatayudEndocrinology and Nutrition Department, Hospital Universitario, Madrid, Spain.
Felicia Alexandra HanzuEndocrinology Hospital Clinic University Barcelona, Barcelona, Spain.
Oscar VidalEndocrine Surgery Department, Hospital Clinic University, Barcelona, Spain.
Marta Araujo-CastroDepartment of Endocrinology and Nutrition, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Cesar Minguez OjedaUrology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Theodosios Papavramidis1st Propedeutic Department of Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Pablo Rodríguez de Vera GómezEndocrinology and Nutrition Department, Hospital Universitario Virgen de la Macarena, Sevilla, Spain.
Abdulaziz AldreesKing Abdulaziz Medical City, Riyadh, Saudi Arabia.
Tariq AltwjryKing Abdulaziz Medical City, Riyadh, Saudi Arabia.
Nuria ValdésDepartment of Endocrinology and Nutrition, Hospital Universitario Cruces, Biobizkaia, Bizkaia CIBERDEM/CIBERER, Endo-ERN, Barakaldo, Spain.
Cristina Álvarez-EscolaEndocrinology and Nutrition Department, Hospital Universitario La Paz, Madrid, Spain.
Iñigo García SanzGeneral and Digestive Surgery Department, Hospital Universitario de La Princesa, Madrid, Spain.
Concepción Blanco CarreraEndocrinology and Nutrition Department, Hospital Universitario Príncipe de Asturias, Madrid, Spain.
Laura Manjón-MiguélezEndocrinology and Nutrition Department, Hospital Universitario Central de Asturias, Oviedo, Spain.
Paz De Miguel NovoaHospital Clínico San Carlos, Madrid, Spain.
Mónica RecasensEndocrinology and Nutrition Department, Institut Català de la Salut Girona, Girona, Spain.
Rogelio García CentenoEndocrinology and Nutrition Department, Hospital Universitario Gregorio Marañón, Madrid, Spain.
Cristina Robles LázaroEndocrinology and Nutrition Department, Hospital Universitario de Salamanca, Salamanca, Spain.
Klaas Van Den HeedeGeneral and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium.
Sam Van SlyckeGeneral and Endocrine Surgery, Onze-Lieve-Vrouw (OLV) Hospital Aalst-Asse-Ninove, Aalst, Belgium.
Theodora MichalopoulouDepartment of Endocrinology and Nutrition, Joan XXIII University Hospital, Tarragona, Spain.
Sebastian AspinallDepartment of General Surgery, Aberdeen Royal Infirmary, Aberdeen, UK.
Ross MelvinDepartment of General Surgery, Aberdeen Royal Infirmary, Aberdeen, UK.
Joel Wen Liang LauDivision of Breast and Endocrine Surgery, Department of General Surgery, Ng Teng Fong General Hospital (NTFGH), National University Health System (NUHS), Singapore, Singapore.
Wei Keat CheahDivision of Breast and Endocrine Surgery, Department of General Surgery, Ng Teng Fong General Hospital (NTFGH), National University Health System (NUHS), Singapore, Singapore.
Man Hon TangDivision of Breast and Endocrine Surgery, Department of General Surgery, Ng Teng Fong General Hospital (NTFGH), National University Health System (NUHS), Singapore, Singapore.
Han Boon OhDivision of Breast and Endocrine Surgery, Department of General Surgery, Ng Teng Fong General Hospital (NTFGH), National University Health System (NUHS), Singapore, Singapore.
John AyukDepartment of Endocrinology, Queen Elizabeth Hospital, Birmingham, UK.
Robert P SutcliffeDepartment of Hepatopancreatobiliary and Liver Transplant Surgery, Queen Elizabeth Hospital, Birmingham, UK.
International Pheo Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe impact of obesity on outcomes after adrenalectomy for pheochromocytoma is unclear. This study aims to evaluate outcomes after minimally invasive and open adrenalectomy for pheochromocytoma in patients with obesity and to determine factors that may affect outcomes. Patients undergoing adrenalectomy for pheochromocytoma in 46 international centers between 2012 and 2022 were reviewed, analyzing baseline information, length of hospital stay (LOS), and postoperative complications. PATIENTS AND

methodsObese (body mass index (BMI) ≥ 30 kg/m

resultsOf the 2016 patients, 639 (31.7%) had obesity. Operative time (110.0 versus 105.0 min; p = 0.467), conversion to open rate (3.1% versus 4.7%; p = 0.079), estimated blood loss (20.0 versus 20.0 ml, p = 0.088), rate of complications (19.3% versus 20.8%; p = 0.425), and CCI were similar. However, patients with obesity required a median of 1 day longer LOS (4.0 days versus 5.0 days; p < 0.001). On multivariable analysis, obesity was not significantly associated with complications or higher CCI. Analyzing solely obese patients, laparoscopic (OR 0.24; p < 0.001) and robotic (OR 0.22; p = 0.011) approaches were independently associated with less morbidity. Additionally, multivariable modeling demonstrated that a retroperitoneal approach in patients with BMI ≥ 30 kg/m

conclusionsObesity does not increase complications or CCI following pheochromocytoma resection, but it does increase LOS. A retroperitoneal approach may uniquely benefit patients with obesity. In view of rising obesity rates, these results warrant further research to validate findings.

Indexed as

AdrenalectomyAdrenal Gland NeoplasmsLaparoscopyObesityPheochromocytomaPostoperative ComplicationsAdultAgedBody Mass IndexFemaleFollow-Up StudiesHumansLength of StayMaleMiddle AgedOperative TimeLaparoscopic adrenalectomyObesityPheochromocytomaPostoperative complicationsRobotic adrenalectomy

Identifiers

PMID39633172

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.