Evidence map›Paper›PMID 39633274›Full record

ArticleBMC infectious diseases2024

Interaction between type 2 diabetes and past COVID-19 on active tuberculosis.

Liz E Calles-Cabanillas, Genesis P Aguillón-Durán, Doris Ayala, José A Caso, Miguel Garza, Mateo Joya-Ayala, America M Cruz-Gonzalez, Raul Loera-Salazar, Ericka Prieto-Martinez, Javier E Rodríguez-Herrera and 5 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Liz E Calles-CabanillasSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
Genesis P Aguillón-DuránSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
Doris AyalaSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
José A CasoSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
Miguel GarzaSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
Mateo Joya-AyalaDepartment of Health and Biomedical Sciences, University of Texas Rio Grande Valley, Edinburg, TX, 78541, USA.
America M Cruz-GonzalezDepartamento Estatal de Micobacteriosis, Secretaría de Salud de Tamaulipas, Reynosa 88630, Matamoros 87370 and Ciudad Victoria 87000, Tamaulipas, México.
Raul Loera-SalazarDepartamento Estatal de Micobacteriosis, Secretaría de Salud de Tamaulipas, Reynosa 88630, Matamoros 87370 and Ciudad Victoria 87000, Tamaulipas, México.
Ericka Prieto-MartinezDepartamento Estatal de Micobacteriosis, Secretaría de Salud de Tamaulipas, Reynosa 88630, Matamoros 87370 and Ciudad Victoria 87000, Tamaulipas, México.
Javier E Rodríguez-HerreraDepartamento Estatal de Micobacteriosis, Secretaría de Salud de Tamaulipas, Reynosa 88630, Matamoros 87370 and Ciudad Victoria 87000, Tamaulipas, México.
Esperanza M Garcia-OropesaUnidad Académica Reynosa-Aztlán, Universidad Autónoma de Tamaulipas, Reynosa, Mexico.
John M ThomasSouth Texas Diabetes and Obesity Institute and Department of Human Genetics, School of Medicine, University of Texas Rio Grande Valley, Edinburg, TX, 78541, USA.
Miryoung LeeSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA.
Jordi B TorrellesPopulation Health and Host Pathogens Interactions Programs and International Center for the Advancement of Research & Education (I•CARE), Texas Biomedical Research Institute, San Antonio, TX, 78229, USA.
Blanca I RestrepoSchool of Public Health, University of Texas Health Science Center at Houston, One West University Blvd, SPH Bldg, Brownsville, TX, 78520, USA. Blanca.i.restrepo@uth.tmc.edu.

Funding

Social stress as a co-morbidity of age-associated tuberculosisP01AG051428 · NIA · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI TURNER, JOANNE · 2016 to 2020
$9.9M
Interdisciplinary NexGen TB research Advancement Center (IN-TRAC)P30AI168439 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI JOANNE TURNER · 2022 to 2026
$6.9M
Bridges to the Baccalaureate Research Training Program at The University of Texas Rio Grande ValleyT34GM137854 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI CHEW, SUE ANNE, GALVEZ, GRISELDA LOPEZ · 2020 to 2024
$1.9M
National Institute of Allergy and Infectious Diseases P30AI168439NIAID NIH HHS P30 AI168439NIA NIH HHS P01 AG051428NIA NIH HHS P01-AG051428NIGMS NIH HHS T34 GM137854NIGMS NIH HHS T34GM137854
6 · The paper itself

Abstract

backgroundThe global setback in tuberculosis (TB) prevalence and mortality in the post-COVID-19 era has been partially attributed to pandemic-related disruptions in healthcare systems. The additional biological contribution of COVID-19 to TB is less clear. The goal of this study was to determine if there is an association between COVID-19 in the past 18 months and a new TB episode, and the role played by type 2 diabetes mellitus (DM) comorbidity in this relationship.

methodsA cross-sectional study was conducted among 112 new active TB patients and 373 non-TB controls, identified between June 2020 and November 2021 in communities along the Mexican border with Texas. Past COVID-19 was based on self-report or positive serology. Bivariable/multivariable analysis were used to evaluate the odds of new TB in hosts with past COVID-19 and/or DM status.

resultsThe odds of new TB were higher among past COVID-19 cases vs. controls, but only significant among DM patients (aOR 2.3). The odds of TB in people with DM was 2.7-fold higher among participants without past COVID-19 and increased to 7.9-fold among those with past COVID-19.

conclusionDM interacts with past COVID-19 synergistically to magnify the risk of TB. Latent TB screening and prophylactic treatment, if positive, is recommended in past COVID-19 persons with DM. Future studies are warranted with a longitudinal design and larger sample size to confirm our findings.

Indexed as

COVID-19Diabetes Mellitus, Type 2TuberculosisAdultAgedComorbidityCross-Sectional StudiesFemaleHumansMaleMexicoMiddle AgedPrevalenceRisk FactorsSARS-CoV-2TexasCOVID-19Cross-sectional studyMexicoTuberculosisType 2 diabetes

Identifiers

PMID39633274
PMCPMC11616277

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.