Evidence map›Paper›PMID 39634892›Full record

ArticlePakistan journal of medical sciences2024

Effect of Anti-VEGF drugs on diabetic Retinopathy-Microaneurysms: A correlation study.

Tianhang Li, Zhaohui Gu, Yueling Zhang, Jie Li, Juan Du, Yan Fu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pakistan journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianhang LiTianhang Li, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.
Zhaohui GuZhaohui Gu, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.
Yueling ZhangYueling Zhang, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.
Jie LiJie Li, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.
Juan DuJuan Du, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.
Yan FuYan Fu, Ward of Ophthalmology 2nd Department, Baoding No.1 Central Hospital, Baoing 071000, Hebei, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the efficacy of anti-vascular endothelial growth factor (VEGF) drugs in diabetic retinopathy (DR)-retinal microaneurysms, and its prognosis. Method: This was a retrospectively study in which total of 120 patients with DR in Baoding No.1 Central Hospital from June 2020 to June 2022 were retrospectively analyzed. According to different treatment methods based on macular edema, they were divided into an injection group and a control group. The control group was treated routinely, while the injection group was additionally intravitreally injected with an anti-VEGF drug. The patients were followed up for one year, and the changes in the number of retinal microaneurysms, best corrected visual acuity (BCVA) and central retinal thickness (CRT) were compared between the two groups. The effect on retinal microaneurysms was analyzed. Result: After treatment for 12 months, the total efficacy of the injection group was 95.00%, which was higher than 80.00% of the control group ( Conclusion: For patients with DR complicated with macular edema, early use of anti-VEGF drugs can significantly improve the fundus lesions, reduce the CRT and number of retinal microaneurysms, and improve the BCVA of the patients, with high clinical efficacy.

Indexed as

Anti-vascular endothelial growth factorBest corrected visual acuityCentral retinal thicknessDiabetic retinopathyMacular edemaMicroaneurysm

Identifiers

PMID39634892
PMCPMC11613385

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.