ArticleNanophotonics (Berlin, Germany)2024
Capillary-assisted flat-field formation: a platform for advancing nanoparticle tracking analysis in an integrated on-chip optofluidic environment.
Article in Nanophotonics (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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6 authors.
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Abstract
Here, we present the concept of flat-field capillary-assisted nanoparticle tracking analysis for the characterization of fast diffusing nano-objects. By combining diffusion confinement and spatially invariant illumination, i.e., flat-fields, within a fiber-interfaced on-chip environment, ultra-long trajectories of fast diffusing objects within large microchannels have been measured via diffraction-limited imaging. Our study discusses the design procedure, explains potential limitations, and experimentally confirms flat-field formation by tracking gold nanospheres. The presented concept enables generating flat-fields in a novel on-chip optofluidic platform for the characterization of individual nano-objects for fundamental light/matter investigations or applications in bioanalytics and nanoscale material science.
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